81 Recruiting Studies at Princess Margaret Cancer Centre
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Toronto, Ontario
All research centersRecruiting Studies at Princess Margaret Cancer Centre
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
Advanced Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Phase II RCT of an Internet-adaptation of Managing Cancer and Living Meaningfully (iCALM)
Advanced Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Phase 2 Study of Pembrolizumab, DPX-Survivac Vaccine and Cyclophosphamide in Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Advanced Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic
Feasibility Study of MET-4: Evaluating Fecal Microbiome Effects in Immunotherapy Patients
All Solid Tumors
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer
Biliary Tract Carcinoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
The Person-centered Evolution of Radiotherapy Services in Ontario Study
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Identification of Patients With Age-Related Clonal Hematopoiesis (ARCH) Among Cancer Survivors
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Comprehensive Health Assessment for my Cancer Treatment Plan
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Magnetic Resonance-Guided Adaptive Radiotherapy (MRgART) Using an Integrated Magnetic Resonance Linear Accelerator (MRL)
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Randomized Controlled Trial of Early Palliative Care for Patients With Advanced Cancer
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors
Glioma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease
Graft Vs Host Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Impact of Cultural and Linguistic Backgrounds on Patient Care and Experience of Women With Gynecologic Malignancies
Gynecologic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)
Hepatocellular Carcinoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person
Lung Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease
Malignancy
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors
Mismatch Repair Proficient Colorectal Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
Dual Tracer (68Ga-DOTATATE and 18F-FDG) PET Imaging in G2 & G3 Gastroenteropancreatic Neuroendocrine Tumors
Neuroendocrine Tumors
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Accelerating Lung Cancer Diagnosis Through Liquid Biopsy
Non-small Cell Lung Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Province of Ontario Strategy for Personalized Management of Pancreatic Cancer Trial
Pancreas Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
FAZA PET/MRI Pancreas
Pancreatic Adenocarcinoma Non-resectable
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic
Study of NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Pancreatic Cancer
Pancreatic Cancer, Advanced or Metastatic
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy
Penile Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
HDR Focal: Feasibility Study
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
"Re-Stimulated" TILs And IL-2 Therapy for Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Recurrent
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Phase 1 Study of RP-6306 With Carboplatin and Paclitaxel in TP53 Ovarian and Uterine Cancer
Recurrent Ovarian Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Binimetinib and Encorafenib for the Treatment of Advanced Solid Tumors With Non-V600E BRAF Mutations
Solid Tumor
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Prospective Analysis of Intestinal Microbiome and Autoimmune Panels as Predictors of Toxicity in ImmunOncology Patients
Solid Tumor
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors
Squamous Cell Cancer of Head and Neck
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
WATChmAN Virtual Testicular Cancer Clinic
Testicular Cancer
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Positioning in RT - Supine vs. Upright
Cancer
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase3 🧠 Behavioral & Psychological Program
Trauma-Focused Managing Cancer And Living Meaningfully (CALM-TF) for Newly Diagnosed and Recurrent Ovarian Cancer
Ovarian Cancer (OvCa)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Samuraciclib in Combination With Gemcitabine/Nab-Paclitaxel in Patients With Metastatic Basal-Like Pancreatic Cancer
Pancreas Ductal Adenocarcinoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
Advanced Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer
Advanced Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Rehab Study for alloBMT Patients
Allogenic Bone Marrow Transplantation
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Study of How Safe and Effective Tarlatamab is in Brain Cancers
Astrocytic Tumor
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma
Bone Sarcoma
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Non-Invasive Artificial Intelligence-Based Platform MonIToring Program (NIP IT!)
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Virtual Rehabilitation for Cancer Survivors
Breast Cancer, Stage 0
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Hypersight and Ethos In Pediatric Radiotherapy
Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Immune Resistance Interrogation Study
Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Genomic Investigation of Unusual Responders
Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Liquid Biopsy Evaluation and Repository Development at Princess Margaret
Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Pembrolizumab With Bendamustine in Hodgkin Lymphoma
Classical Hodgkin Lymphoma
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host
Colorectal Neoplasms
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG PET and ctDNA to Optimize Primary Therapy of DLBCL (GRAIL)
Diffuse Large B Cell Lymphoma (DLBCL)
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta
DLBCL - Diffuse Large B Cell Lymphoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
PET-MRI Esophagus Feasibility Study
Esophagogastric Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Study of Biomarkers in Gynecological Cancers
Gynecologic Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Study to Assess the Safety and Effects of Porphysome Nanoparticles for Imaging in Gynaecological Cancers
Gynecological Cancers
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
HN-QUEST: A Study of Head and Neck Imaging Biomarkers
Head and Neck Squamous Cell Carcinoma
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Cabozantinib to Treat Recurrent Liver Cancer Post Transplant
Hepatocellular Carcinoma
View Study & Checklist ➔ 🟢 Recruiting Phase3 📋 Clinical Research Protocol
Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction
Liver Metastases
View Study & Checklist ➔ 🟢 Recruiting Phase2 📋 Clinical Research Protocol
A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment
Locally Advanced Pancreatic Adenocarcinoma
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC
Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
R-RPLND as First-line Treatment for Clinical Stage IIA/B Testicular Seminoma
Lymphadenopathy Retroperitoneal
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Patient Reported Outcomes/Metrics Program Trial
Metastatic Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Plan Development for Giving Teclistamab in the Outpatient Setting
Multiple Myeloma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Early Palliative Care for Patients With Multiple Myeloma and Aggressive Lymphoma
Multiple Myeloma in Relapse
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy
Myelodysplastic Syndrome
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms
Myeloproliferative Neoplasm
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Using ctDNA to Determine Therapies for Lung Cancer
Non Small Cell Lung Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
STEP2 vs. Routine Early Palliative Care: Randomized Noninferiority Trial
Oncology
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Durvalumab and Oleclumab in Resectable PDAC
Pancreatic Ductal Adenocarcinoma
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Using Tumor Models to Determine Treatments
Pancreatic Ductal Carcinoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Feasibility of CALM in Patients With Ovarian Cancer
Patient Satisfaction
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Myeloproliferative Neoplasms (MPNs) Patient Registry
Primary Myelofibrosis
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response
Prostate Adenocarcinoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
A Pan-Canadian, Investigator Initiated Clinical Trial With Focal IRE Directed to Intermediate-Risk Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Remote Monitoring of Patient Reported Outcomes to Improve the Efficacy of the Acute Phase Radiotherapy Review Process
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Salvage MR-guided High-Dose-Rate Brachytherapy for Prostate Bed Recurrence After Radiotherapy in the PSMA PET Scan Era
Prostate Cancer Recurrent
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
A Comprehensive Multiomic Biomarker Evaluation Across Two Single-arm Cohorts to Elucidate Mechanisms of Response and Resistance in Recurrent/Metastatic (R/M) Head and Neck Squamous Cell Carcinoma (HNSCC)
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL
Relapsed or Refractory CD19+ B-cell Lymphoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Circulating Tumor DNA in Soft Tissue Sarcoma
Soft Tissue Sarcoma
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
LANDscape MApping of Epitopes and T Cell Receptors for Selected Cancers
Solid Tumor
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer
Squamous Cell Cancer of Head and Neck (SCCHN)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers
Squamous Cell Carcinoma of Head and Neck
View Study & Checklist ➔