100 Recruiting Studies at Mayo Clinic
Active clinical trials at this research center, sourced directly from the NIH registry.
π Phoenix, Arizona
All research centersRecruiting Studies at Mayo Clinic
π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic
A Phase 1 Study of BMF-500 in Adults With Acute Leukemia
Acute Myeloid Leukemia
View Study & Checklist β π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic
Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)
Advanced or Metastatic NSCLC
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
Advanced Solid Tumor
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)
ALS
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Personalized Antisense Oligonucleotide Therapy for A Single Participant With CHCHD10 ALS
Amyotrophic Lateral Sclerosis
View Study & Checklist β π΅ Active, Not Recruiting Phase2 / Phase3 π Investigational Drug / Biologic
SHAPE Neoadjuvant Chemotherapy Response
Anatomic Stage III Breast Cancer AJCC v8
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π Clinical Research Protocol
Realtime Diagnosis From Electrocardiogram Artificial Intelligence-Guided Screening for Atrial Fibrillation With Long Follow-Up (REGAL)
Atrial Fibrillation
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Personalized Antisense Oligonucleotide Therapy for A Single Participant With LMNB1 Mutation Associated Autosomal Dominant Leukodystrophy (ADLD)
Autosomal Dominant Leukodystrophy
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Role of ROS and cAMP-PKA Biomarkers in ADPKD
Autosomal Dominant Polycystic Kidney Disease
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Intrarenal Microvasculature in ADPKD
Autosomal Dominant Polycystic Kidney Disease
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD
Autosomal Dominant Polycystic Kidney Disease
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Evaluating Bladder CAREβ’, a New Non-Invasive Urine Test, for Bladder Cancer Detection in Inconclusive Cases
Bladder Cancer
View Study & Checklist β π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic
A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-GuΓ©rin (BCG) in Participants With BCG-naΓ―ve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)
Bladder Cancer
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Genetic Risk Estimations for Influencing Decision Making in Women at High Risk of Breast Cancer, GENRE 2 Study
Breast Cancer
View Study & Checklist β π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic
The HeLiX (Hemorrhage During Liver Resection: traneXamic Acid) Trial
Cancer
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
9-ING-41 in Patients With Advanced Cancers
Cancer
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
A Study of Electrocardiogram and Focused Cardiac Ultrasound for Enhanced Cardiac Disease Screening
Cardiac Disease
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Evaluation of Plasma Renin Concentrations in Cardiac Surgery
Cardiac Surgery With Cardiopulmonary Bypass
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality
Colon Cancer
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System
Colorectal Lesion
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Transforaminal Lumbar Interbody Fusion (TLIF)
Degenerative Disease of the Lumbosacral Spine
View Study & Checklist β π΅ Active, Not Recruiting Phase2 / Phase3 π Investigational Drug / Biologic
A Study of AL102 in Patients With Progressing Desmoid Tumors
Desmoid
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Surface EMG Testing on Swallowing in EoE Patients
Eosinophilic Esophagitis (EoE)
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Neural Circulatory Control and SUDEP Risk.
Epilepsy
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Acute Recording of Stereotyped High-Frequency Oscillations
Epilepsy
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Cohort Study of Pancreatic Cancer Risk
Familial Pancreatic Cancer
View Study & Checklist β π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
Gastric Cancer
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency
Gene Mutations
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Optimizing Y90 Therapy for Radiation Lobectomy
HCC
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
A Study of Adipose Tissue in Adaptive Responses to Exercise
Healthy
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study
Heart Failure
View Study & Checklist β π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic
A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers
HPV-Related Carcinoma
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Graded Exercise Hypoxia Testing
Hypoxia
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
Improving Implementation of Evidence-based Approaches and Surveillance to Prevent Bacterial Transmission and Infection
Infection
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
LLLT to Reduce Low Back Pain
Low Back Pain
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas
Malignant Glioma
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Satisfaction and Feasibility Evaluation of an Electronic Massager Compared to Massage Therapist-delivered Massage
Massage Therapy
View Study & Checklist β π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic
A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma
Multiple Myeloma
View Study & Checklist β π΅ Active, Not Recruiting Phase1 π Investigational Drug / Biologic
Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma
Multiple Myeloma
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy
Multiple System Atrophy
View Study & Checklist β π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic
A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA)
Multiple System Atrophy
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Natural History of Shoulder Pathology in Manual Wheelchair Users
Paraplegia
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Intraoperative Costs and Patient Perceptions in Sacrocolpopexy for Prolapse
Pelvic Organ Prolapse
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab (Phase 1a) and Pegylated Liposomal Doxorubicin (Phase 1b) as Treatment for Ovarian Cancer.
Platinum-refractory Ovarian Carcinoma
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Platinum-Resistant Fallopian Tube Carcinoma
View Study & Checklist β π΅ Active, Not Recruiting Phase2 / Phase3 π Investigational Drug / Biologic
A Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With PLD
Polycystic Liver Disease
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome
Polycystic Ovarian Syndrome
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
Improving Voice Production for Adults With Age-related Dysphonia
Presbylarynx
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π Clinical Research Protocol
Prostate Imaging Using MRI +/- Contrast Enhancement
Prostate Cancer
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π Clinical Research Protocol
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
Psoriasis
View Study & Checklist β π΅ Active, Not Recruiting Phase3 π Investigational Drug / Biologic
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
Pulmonary Disease, Chronic Obstructive
View Study & Checklist β π΅ Active, Not Recruiting Phase3 βοΈ Medical Device Protocol
Pivotal Study of Voro Urologic Scaffold
Radical Prostatectomy
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Ph I/II Trial of Systemic VSV-IFNΞ²-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors
Solid Tumor
View Study & Checklist β π΅ Active, Not Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
GEN1046 Safety Trial in Patients With Malignant Solid Tumors
Solid Tumors
View Study & Checklist β π΅ Active, Not Recruiting Phase2 π Investigational Drug / Biologic
A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)
Solid Tumours Harboring NRG1 Fusion
View Study & Checklist β π΅ Active, Not Recruiting Observational / Diagnostic π©Ί Clinical Procedure Protocol
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
Uterine Prolapse
View Study & Checklist β π΅ Active, Not Recruiting Interventional Protocol π Observational Clinical Research
Polyethylene Wear Particle Analysis of TKA
Wear of Articular Bearing Surface of Prosthetic Joint
View Study & Checklist β π‘ Not Yet Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
A Study Of Surgical Repair Of Discontinuous Branching Pulmonary Arteries
Absent Pulmonary Artery
View Study & Checklist β π‘ Not Yet Recruiting Phase2 π Investigational Drug / Biologic
Dose Schedule Study of BCMA Bispecific Antibody, Elranatamab, for Newly Diagnosed Immunoglobulin Light Chain (AL) Amyloidosis
Amyloid Light-chain Amyloidosis
View Study & Checklist β π‘ Not Yet Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Personalized Antisense Oligonucleotide Therapy for A Single Patient With CHCHD10 ALS (nL18576)
Amyotrophic Lateral Sclerosis
View Study & Checklist β π‘ Not Yet Recruiting Phase3 π Investigational Drug / Biologic
A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.
Coronary Artery Disease (CAD)
View Study & Checklist β π‘ Not Yet Recruiting Interventional Protocol π Observational Clinical Research
C11 ER176 PET in Evaluating Neuroinflammation in Patients With Post-COVID Syndrome
COVID-19
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Transverse Tibial Bone Transport (TTT) in the Management of Chronic Diabetic Lower Extremity Wounds
Diabetic Foot Ulcer
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations
Epilepsy
View Study & Checklist β π‘ Not Yet Recruiting Phase3 π Investigational Drug / Biologic
Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma
Gastric / Gastroesophageal Junction Adenocarcinoma
View Study & Checklist β π‘ Not Yet Recruiting Phase2 π Investigational Drug / Biologic
Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas
Glioblastoma
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, Biomechanics, and Pain Intensity
Gluteus Medius Muscle Strength
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
Meaning-Centered Psychotherapy for Addressing Existential Distress of Patient/Caregiver Dyads Following Hematopoietic Stem Cell Transplantation: Feasibility and Acceptability
Hematopoietic Stem Cell Transplant
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
MenoZen VR for Menopause Symptom Management: Phase 2
Menopause
View Study & Checklist β π‘ Not Yet Recruiting Phase4 π Investigational Drug / Biologic
A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical Patients
Metabolic Acidosis
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial
Migraine
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π©Ί Clinical Procedure Protocol
The Effect of Dry Needling With Electrical Stimulation on Individuals With Restless Legs Syndrome
Neck Pain
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π§ Behavioral & Psychological Program
Remote Assessment of Digital Neurologic Testing
Neurology
View Study & Checklist β π‘ Not Yet Recruiting Phase2 π Investigational Drug / Biologic
nVNS, CBD, and SoC for Persistent Post-Traumatic Headache
Persistent Post Traumatic Headache
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π Investigational Drug / Biologic
Arm Elevation for Prevention of Propofol Injection Pain
Propofol Injection Pain
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π Clinical Research Protocol
Mechanisms of Resistance Exercise Training for Improved Muscle Insulin Sensitivity
Resistance Training
View Study & Checklist β π‘ Not Yet Recruiting Phase1 π Investigational Drug / Biologic
A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations
Solid Tumors With FGFR2 Alterations, Adult
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic π Clinical Research Protocol
Effects of a Mobile App-Based Mindfulness Intervention in Persons With Spinal Cord Injury and Chronic Pain
Spinal Cord Injuries
View Study & Checklist β π‘ Not Yet Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Dorsal Root Ganglion Stimulation After Lower Motor Neuron Damage
Spinal Cord Injuries
View Study & Checklist β π‘ Not Yet Recruiting Interventional Protocol π Observational Clinical Research
Precision Medicine for Indolent Systemic Mastocytosis (PRISM)
Systemic Mastocytosis
View Study & Checklist β π‘ Not Yet Recruiting Interventional Protocol π Observational Clinical Research
Comparison of Ultrasound and Anatomic Landmark Techniques of the Ulnar and Posterior Tibial Nerves
Ulnar Nerve
View Study & Checklist β π‘ Not Yet Recruiting Interventional Protocol π Observational Clinical Research
The Mayo Clinic Rare and Undiagnosed Disease Hackathon
Undiagnosed Diseases
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
24-Hydroxylase Deficiency and CYP24A1 Mutation Patient Registry
24-hydroxylase Deficiency
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
A Prospective Research Investigation of Ischemia Using MCG
Acute Coronary Syndrome
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
Registry of Patients Prescribed Anticoagulation
Acute Deep Vein Thrombosis
View Study & Checklist β π’ Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
Acute Kidney Injury
View Study & Checklist β π’ Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
Advanced Cancer
View Study & Checklist β π’ Recruiting Phase1 π Investigational Drug / Biologic
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor
Advanced Liver Cancer
View Study & Checklist β π’ Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Advanced or Metastatic Solid Tumors
View Study & Checklist β π’ Recruiting Phase1 π Investigational Drug / Biologic
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
Advanced Solid Tumor
View Study & Checklist β π’ Recruiting Phase1 / Phase2 π Investigational Drug / Biologic
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Advanced Solid Tumors
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
Mechanisms of Anabolic Resistance in Older Humans
Aging
View Study & Checklist β π’ Recruiting Phase4 π Investigational Drug / Biologic
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
Alzheimer Disease
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography
Amyloidosis
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
Exactech Vantage Total Ankle System Post Market Clinical Follow-Up - US Only
Ankle Rheumatoid Arthritis
View Study & Checklist β π’ Recruiting Observational / Diagnostic βοΈ Medical Device Protocol
Prospective Evaluation of Physician Modified Endografts for Aortic Disease
Aortic Aneurysm
View Study & Checklist β π’ Recruiting Interventional Protocol π Observational Clinical Research
Clinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms
Aortic Aneurysm, Abdominal
View Study & Checklist β