Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors (NCT05394103)
A Phase 1/2 Multicenter, Open-label, Dose-escalation, Safety, Pharmacodynamic, and Pharmacokinetic Study of Q901Administered Via Intravenous Infusion as Monotherapy and in Combination With Pembrolizumab in Adult Patients With Selected Advanced Solid Tumors With Cohort Expansions at the Recommended Phase 2 Dose
🩺 Plain-English Summary (8th-Grade Level)
Multicenter, open-label, dose-escalation, safety, tolerability, PK and pharmacodynamic study with a dose expansion at the RP2D to evaluate safety and potential antitumor activity of Q901 as a monotherapy and in combination with pembrolizumab
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (11 Sites)
- Mayo Clinic — Phoenix, Arizona
- University of Southern California — Los Angeles, California
- Mayo Clinic — Jacksonville, Florida
- Northwestern University — Chicago, Illinois
- Mayo Clinic — Rochester, Minnesota
- Atlantic Health System Hospital — Morristown, New Jersey
- Mary Crowley Cancer Research — Dallas, Texas
- National Cancer Center — Goyang-si,
- CHA University Bundang Medical Center — Seongnam-si,
- Asan Medical Center — Seoul,
- Severance Hospital — Seoul,
📞 Contact the Study Coordinator
Phone: +82-31-8060-1610
Email: clinicaltrial_info@qurient.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.