nVNS, CBD, and SoC for Persistent Post-Traumatic Headache (NCT07624279)
A Phase 2 Randomized, Multicenter Study of Non-Invasive Vagus Nerve Stimulation (nVNS), Cannabidiol, and Standard of Care for the Treatment of Persistent Post-Traumatic Headache in Elite Athletes
🩺 Plain-English Summary (8th-Grade Level)
Do cannabidiol (CBD) or vagus nerve stimulation reduce the frequency of persistent post-traumatic headache more than traditional oral headache medications?
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic — Scottsdale, Arizona
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- Mayo Clinic — Scottsdale, Arizona
- Kerlan-Jobe Orthopaedic Institute — Los Angeles, California
- International Spine, Pain & Performance Center — Washington D.C., District of Columbia
- Florida Spine & Pain Specialists — Tampa, Florida
- University of Kansas Medical Center — Kansas City, Kansas
- Premier Pain Center — Shrewsbury, New Jersey
- University Hospitals Cleveland Medical Center — Cleveland, Ohio
- Allegheny General Hospital — Pittsburgh, Pennsylvania
📞 Contact the Study Coordinator
Phone: (858) 249-3800
Email: nmschuster@health.ucsd.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Persistent Post Traumatic Headache clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.