14 Recruiting Sickle Cell Disease Phase 1 / Phase 2 Clinical Trials
Active phase 1 / phase 2 studies for sickle cell disease enrolling across the USA. Verify eligibility and contact site coordinators.
All Sickle Cell Disease studiesPhase 1 / Phase 2 Studies for Sickle Cell Disease
BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease
📍 University of Alabama at Birmingham — Birmingham, Alabama
View Study & Checklist ➔Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)
📍 UCSF Benioff Children's Hospital — Oakland, California
View Study & Checklist ➔Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)
📍 University of Illinois at Chicago — Chicago, Illinois
View Study & Checklist ➔Feasibility and Acceptability of Amani
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease
📍 Children's Hospital Los Angeles — Los Angeles, California
View Study & Checklist ➔A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
📍 University of Alabama Birmingham — Birmingham, Alabama
View Study & Checklist ➔Cannabidiol in Sickle Cell Disease
📍 Icahn School of Medicine at Mount Sinai — Manhattan, New York
View Study & Checklist ➔Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease
📍 University of California, Los Angeles — Los Angeles, California
View Study & Checklist ➔Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease
📍 Children's Hospital of Colorado — Aurora, Colorado
View Study & Checklist ➔Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease
📍 Children's Healthcare fo Atlanta at Hughes Spalding — Atlanta, Georgia
View Study & Checklist ➔