37 Paid Clinical Research Studies in Chapel Hill, North Carolina
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL
The body has different ways of fighting infection and disease. No single way is effective at fighting cancer. This research study combines two different ways of fighting disease: a
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Hispanic Community Health Study / Study of Latinos
The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a multi-center epidemiologic study in Hispanic/Latino populations to determine the role of acculturation in the
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔mPATH-Cloud for Colorectal Cancer Screening
This study assesses the effectiveness of colorectal cancer (CRC) screening intervention, mobile Patient Technology for Health (mPATH™-Cloud), compared to usual care among subjects
📍 Lineberger Comphrehensive Cancer Center at University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Water From Bottles to Establish Strong Teeth
The waterBEST study is a proof-of-concept, randomized, double-masked, placebo controlled, parallel group study evaluating dental caries-preventive effects of fluoridated bottled wa
📍 Division of Pediatric and Public Health, UNC Adams School of Dentistry — Chapel Hill, North Carolina
View Study & Checklist ➔Dupilumab for Eosinophilic Esophagitis With Severe Strictures
The purpose of this research study is to determine how well an FDA-approved drug, dupilumab, works to treat patients with severe strictures and active Eosinophilic Esophagitis (EoE
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian
This is single center, open-label phase 1 dose escalation trial that uses modified 3+3 design to identify a recommended phase 2 dose (RP2D) of CAR.B7-H3 T cell product. An expansio
📍 Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina
View Study & Checklist ➔Impact of Financial Incentives
This trial will look at the impact of clinic-level financial incentives to improve provider communication and increase HPV vaccine uptake. Some clinics will receive communication t
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Human Autologous Lung Stem Cell Transplant for Idiopathic Pulmonary Fibrosis
Purpose: To demonstrate the safety and efficacy of autologous Lung Spheroid Stem Cells (LSCs) administered by intravenous infusion in patients with idiopathic pulmonary fibrosis P
📍 University of North Carolina as Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL
The body has different ways of fighting infection and disease. No single way is perfect for fighting cancer. This research study combines two different ways of fighting disease: an
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
This research study combines 2 different ways of fighting disease: antibodies and T cells. Both antibodies and T cells have been used to treat patients with cancers, and both have
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL
The body has different ways of fighting infection and disease. No single way seems perfect for fighting cancer. This research study combines two different ways of fighting disease:
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine
This study is designed to test the feasibility and preliminary efficacy of a continuous glucose monitor (CGM)-augmented food is medicine (FIM) intervention for adults with type 2 d
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program
The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss a
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology
The purpose of this study is to investigate how collecting information about treatment-related side effects directly from patients can help manage the side effects associated with
📍 Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina
View Study & Checklist ➔REAL-Fam Feasibility Study for Youth Diabetes Management
The goal of this clinical trial is to learn if the REAL-Fam occupational therapy intervention is feasible to study in a larger-scale randomized controlled trial. It will also seek
📍 The University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults. Though numerous
📍 UNC-Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Treating Binge Eating and Obesity Digitally in Women
More than 30% of Black women with obesity binge eat. Binge eating may increase the risk for the development of metabolic syndrome and binge-eating-disorder (BED), which is associat
📍 UNC-Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔A Targeted Electronic Health Approach to Reduce Fear of Recurrence in Breast Cancer Survivors (FoRtitude)
The goal of this study is to determine if the intervention or if general information about being a breast cancer survivor can help Breast Cancer Survivors reduce their fear of recu
📍 UNC Chapel Hill School of Medicine Public Health — Chapel Hill, North Carolina
View Study & Checklist ➔Developing and Strengthening Cannabis Warnings: Warning Message Testing
The purpose of this activity is to identify promising cannabis warning messages from different themes. Participants will be adults who live in the United States, including both peo
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts
The goal of this study is to explore cognitive burden perceptions among physicians in relation to case report writing. Furthermore, this study evaluates the use of artificial intel
📍 Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina
View Study & Checklist ➔The PharmFIT Study
This study will conduct a randomized controlled trial to assess the impact of a pharmacy-based FIT intervention, Pharmacy-based FIT (PharmFIT), on colorectal cancer screening (CRC)
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Teen Vulnerability to Irritability: Brain and Estrogen Changes
Purpose: Risk of severe psychopathology increases dramatically during adolescence, especially for females. Changes in ovarian steroids across the menstrual cycle produce windows of
📍 Biomedical Research Imaging Center (BRIC) at UNC — Chapel Hill, North Carolina
View Study & Checklist ➔Daily Upgrade Trial
This study evaluates the acute and chronic effects of an essential amino acid supplement (Daily Upgrade EAA+) on metabolomics, amino acid kinetics, metabolic rate, body composition
📍 Applied Physiology Laboratory — Chapel Hill, North Carolina
View Study & Checklist ➔Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML
This study is testing a new treatment combination called RAVEN, which includes revumenib, azacitidine, and venetoclax, in patients who are newly diagnosed with a specific type of a
📍 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma
The goal of this study is to learn whether children, adolescents, and young adults with newly diagnosed high-grade osteosarcoma can be safely discharged from the hospital at slight
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Optimization of Dietary Adherence in a Mobile Weight Loss Intervention
The goal of this study is to test multiple individual treatment components added to a 6-month standard mobile behavioral weight loss program that are intended to help participants
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Mast Cell Treatment in Post-tick Bite Illness (PTBI)
This is a Phase II double-blinded study to assess the safety, tolerability, and feasibility of the mast cell stabilizing medications ketotifen and cromolyn compared to participants
📍 University of North Carolina — Chapel Hill, North Carolina
View Study & Checklist ➔Characterization of Doxycycline Pharmacokinetics and Adherence
The purpose of this study is to evaluate the effect of body changes on doxycycline concentrations for different dosing schedules. This study will involve a single dose phase and a
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to
📍 Carolina Crossing B, Suite 1 — Chapel Hill, North Carolina
View Study & Checklist ➔Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
This project will compare two training models of an evidence-based online dementia care training program for direct care staff in assisted living to a waitlist control: 1) essentiA
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Stress Trajectories and Anhedonia in Adolescence Research Study
This project will examine how multiple biological measures from the brain and the body's stress response system contribute to anhedonia (the loss of pleasure) in adolescence. The g
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Eating Disorders Genetics Initiative 2
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrollin
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Adverse Adolescent Pathways to Substance Use
Purpose: This 5-year R01 study will elucidate the role of maturational change across adolescence in neural connectivity and physiological stress responses in the relationship betwe
📍 The University of North Carolina at Chapel Hill School of Medicine — Chapel Hill, North Carolina
View Study & Checklist ➔Animal Assisted Therapy in Pediatric Dentistry
A prospective randomized trial measuring physiologic biometrics and perceptions of stress during a pediatric dental exam, cleaning, and simulated radiographs with or without a ther
📍 General & Oral Health Center — Chapel Hill, North Carolina
View Study & Checklist ➔AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation
This study will test how well an artificial intelligence (AI) software called Aorta AIM measures the size of the aorta (the body's main blood vessel) from CT scans. The aorta can b
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Affect-based Impulsivity in Borderline Personality Disorder
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old. The main q
📍 University of North Carolina at Chapel Hill — Chapel Hill, North Carolina
View Study & Checklist ➔Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
This is a 4-arm, single-center study involving 40 participants. Ten healthy volunteers will be enrolled for system imaging optimization, and thirty (30) patients with previously id
📍 The University of North Carolina — Chapel Hill, North Carolina
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