High-Dose Interferon Alfa in Treating Patients With Stage II or Stage III Melanoma (NCT00003641)
Phase III Randomized Study of Four Weeks of High Dose Interferon Alfa-2b in Stage T2bN0, T3a-bN0, T4a-bN0, and T1-4, N1a,2a (Microscopic) Melanoma
🩺 Plain-English Summary (8th-Grade Level)
RATIONALE: Interferon alfa may interfere with the growth of cancer cells. It is not yet known whether treatment with interferon alfa is more effective than observation alone for stage II or stage III melanoma that has been completely removed surgically. PURPOSE: This randomized phase III trial is studying high dose interferon alfa to see how well it works compared to observation only in treating patients with stage II or stage III melanoma that has been completely removed by surgery.
Who can join: Review the eligibility criteria below.
Location: UAB Comprehensive Cancer Center — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (533 Sites)
Showing the first 25 of 533 sites.
- UAB Comprehensive Cancer Center — Birmingham, Alabama
- University of South Alabama Mitchell Cancer Institute — Mobile, Alabama
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas
- Kaiser Permanente - Deer Valley — Antioch, California
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California
- Peninsula Medical Center — Burlingame, California
- Southern California Permanente Medical Group — Downey, California
- Kaiser Permanente - Fremont — Fremont, California
- Marin Cancer Institute at Marin General Hospital — Greenbrae, California
- Kaiser Permanente Medical Center - Hayward — Hayward, California
- Loma Linda University Cancer Institute at Loma Linda University Medical Center — Loma Linda, California
- Kaiser Permanente Medical Center - Oakland — Oakland, California
- Veterans Affairs Medical Center - Palo Alto — Palo Alto, California
- Kaiser Permanente Medical Center - Redwood City — Redwood City, California
- Kaiser Permanente Medical Center - Richmond — Richmond, California
- Kaiser Permanente Medical Center - Roseville — Roseville, California
- Sutter Cancer Center at Roseville Medical Center — Roseville, California
- Sutter Cancer Center — Sacramento, California
- South Sacramento Kaiser-Permanente Medical Center — Sacramento, California
- Kaiser Permanente Medical Center - Sacramento — Sacramento, California
- Kaiser Permanente Medical Office -Vandever Medical Office — San Diego, California
- Naval Medical Center - San Diego — San Diego, California
- Kaiser Permanente Medical Center - San Francisco Geary Campus — San Francisco, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Melanoma (Skin)
- Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma — Tampa, Florida
- A Study to Test the Benefit of Vitamin B5 in Patients With Melanoma — Toronto, Ontario
- Zr89 + PET Companion Trial — Philadelphia, Pennsylvania
- Fianlimab&Cemiplimab as TotalNeoadj The (TNT) ForMelanoma — Orange, California
- A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors — La Jolla, California
Explore by condition: All Melanoma (Skin) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.