Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery (NCT00334815)
A Pilot Trial of Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Docetaxel and the Addition of Bevacizumab (NSC-704865) in Three Cohorts of Patients With Inoperable Locally Advanced Stage III Non-small Cell Lung Cancer
🩺 Plain-English Summary (8th-Grade Level)
This clinical trial studies combination chemotherapy, radiation therapy, and bevacizumab in treating patients with newly diagnosed stage III non-small cell lung cancer that cannot be removed by surgery. Drugs used in chemotherapy, such as cisplatin, etoposide, and docetaxel, work in different ways to stop the growth of \[cancer/tumor\] cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells. Monoclonal antibodies, such as bevacizumab, may interfere with the ability of tumor cells to grow and spread. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy) together with radiation therapy and bevacizumab may kill more tumor cells.
Who can join: Review the eligibility criteria below.
Location: Providence Hospital — Mobile, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (61 Sites)
Showing the first 25 of 61 sites.
- Providence Hospital — Mobile, Alabama
- Saint Bernards Regional Medical Center — Jonesboro, Arkansas
- University of Arkansas for Medical Sciences — Little Rock, Arkansas
- Highlands Oncology Group - Rogers — Rogers, Arkansas
- USC / Norris Comprehensive Cancer Center — Los Angeles, California
- Fremont - Rideout Cancer Center — Marysville, California
- UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California
- University of California Davis Comprehensive Cancer Center — Sacramento, California
- Providence Santa Rosa Memorial Hospital — Santa Rosa, California
- Gene Upshaw Memorial Tahoe Forest Cancer Center — Truckee, California
- Northbay Cancer Center — Vacaville, California
- Rocky Mountain Regional VA Medical Center — Aurora, Colorado
- UCHealth University of Colorado Hospital — Aurora, Colorado
- Denver Health Medical Center — Denver, Colorado
- Shaw Cancer Center — Edwards, Colorado
- Valley View Hospital Cancer Center — Glenwood Springs, Colorado
- Montrose Memorial Hospital — Montrose, Colorado
- Cancer Centers of Central Florida PA — Leesburg, Florida
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler — Savannah, Georgia
- Loyola University Medical Center — Maywood, Illinois
- Edward Hospital/Cancer Center — Naperville, Illinois
- HaysMed — Hays, Kansas
- Hutchinson Regional Medical Center — Hutchinson, Kansas
- University of Kansas Cancer Center — Kansas City, Kansas
- Olathe Cancer Center — Olathe, Kansas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.