Multicenter ACL Revision Study (MARS) (NCT00625885)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL) reconstruction. The investigators hypothesize that modifiable variables exist at the time of revision ACL reconstruction (e.g., cause of failure, current graft source and type, surgical exposure, and femoral and tibial tunnel position) which will be predictors of patient-reported outcomes.
Who can join: Review the eligibility criteria below.
Location: Scripps Memorial Hospital (OrthoCal Healthcare) — La Jolla, California
Age range: 12 Years to 65 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (49 Sites)
Showing the first 25 of 49 sites.
- Scripps Memorial Hospital (OrthoCal Healthcare) — La Jolla, California
- University of California - Los Angeles (UCLA) — Los Angeles, California
- University of California - San Francisco — San Francisco, California
- Orthopaedic Associates of Aspen and Glenwood — Aspen, Colorado
- University of Colorado — Boulder, Colorado
- Connecticut Children's Medical Center — Farmington, Connecticut
- University of Connecticut Health Center — Farmington, Connecticut
- UHZ Sports Medicine Institute — Coral Gables, Florida
- Intermountain Orthopaedics — Boise, Idaho
- Rush University Medical Center — Chicago, Illinois
- Methodist Sports Medicine Center — Indianapolis, Indiana
- University of Iowa — Iowa City, Iowa
- Cheaspeake Orthopaedics and Sports Medicine Center — Glen Burnie, Maryland
- Beth Israel Deaconess Medical Center — Boston, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Mayo Clinic — Rochester, Minnesota
- Regions Hospital (Health Partners Research Foundation) — Saint Paul, Minnesota
- Washington University at St. Louis — St Louis, Missouri
- Bridger Orthopaedic and Sports Medicine — Bozeman, Montana
- New Hamphsire Knee Center — Holderness, New Hampshire
- Robert Wood Johnson Medical School — New Brunswick, New Jersey
- Princeton Orthopaedic Associates — Princeton, New Jersey
- University of Buffalo — Buffalo, New York
- NYU School of Medicine — New York, New York
- Hospital for Special Surgery — New York, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Rupture of Anterior Cruciate Ligament
- Multicenter Orthopaedics Outcomes Network for ACL Reconstructions — Boulder, Colorado
Explore by condition: All Rupture of Anterior Cruciate Ligament clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.