๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-24

Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases (NCT00920972)

A Study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-Malignant Disease Using a Reduced-Intensity Preparatory Regime

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Washington University School of Medicine

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.

Who can join: Review the eligibility criteria below.

Location: Phoenix Children's Hospital โ€” Phoenix, Arizona

Age range: Not specified to 20 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (28 Sites)

Showing the first 25 of 28 sites.

  • Phoenix Children's Hospital โ€” Phoenix, Arizona
  • Children's Hospital of Orange County โ€” Orange, California
  • University of California โ€” San Diego, California
  • Yale School of Medicine โ€” New Haven, Connecticut
  • George Washington University School of Medicine โ€” Washington D.C., District of Columbia
  • Nemours Children's Health โ€” Jacksonville, Florida
  • University of Miami โ€” Miami, Florida
  • Miami Children's Hospital โ€” Miami, Florida
  • All Children's Hospital โ€” St. Petersburg, Florida
  • Children's Memorial Hospital โ€” Chicago, Illinois
  • Indiana University School of Medicine โ€” Indianapolis, Indiana
  • Children's Hospital of New Orleans โ€” New Orleans, Louisiana
  • Children's Mercy โ€” Kansas City, Missouri
  • St. Louis University โ€” St Louis, Missouri
  • Washington University School of Medicine (in St. Louis) โ€” St Louis, Missouri
  • Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Columbia University Medical Center โ€” New York, New York
  • University of North Carolina โ€” Chapel Hill, North Carolina
  • Carolinas Medical Center โ€” Charlotte, North Carolina
  • Duke Children's Hospital โ€” Durham, North Carolina
  • The University of Oklahoma โ€” Oklahoma City, Oklahoma
  • University of Pittsburg โ€” Pittsburgh, Pennsylvania
  • Cook Children's Hospital โ€” Forth Worth, Texas
  • Texas Transplant Institute โ€” San Antonio, Texas
  • University of Utah โ€” Salt Lake City, Utah

๐Ÿ“ž Contact the Study Coordinator

Phone: (314) 286-1168

Email: kellerl@wustl.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—