Nashville Early Diagnosis Lung Cancer Project (NCT01475500)
🩺 Plain-English Summary (8th-Grade Level)
This screening study will address the lack of molecular strategies for the early detection of lung cancer and integrate those with epidemiological and imaging strategies. The hypothesis is that the repeated measure of biomarkers of risk obtained from the molecular analysis of biological specimens including those from bronchoscopy (bronchial brushings and biopsies) may contribute to the refinement of high-risk populations and allow an earlier clinical diagnosis. The goal of the investigators study is to provide screening for lung cancer in a high-risk population. In this prospective cohort it will be tested whether repeated measure of biomarkers of risk allows early detection of lung cancer.
Who can join: Review the eligibility criteria below.
Location: Veterans Administration — Nashville, Tennessee
Age range: 55 Years to 80 Years
🧪 Interventions in This Study
- Sputum sample (PROCEDURE)
- Pulmonary function tests (PROCEDURE)
- Computerized tomography (CT) scan of the chest (RADIATION)
- Buccal epithelium collection (OTHER)
- Nasal brushings (PROCEDURE)
- Bronchoscopy (PROCEDURE)
- Bronchoalveolar lavage (PROCEDURE)
- Blood sample collection (PROCEDURE)
- Urine sample (PROCEDURE)
- Questionnaire-data collection (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- Veterans Administration — Nashville, Tennessee
- Vanderbilt University, Vanderbilt-Ingram Cancer Center — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Lung Cancer
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- Early Detection of Lung Cancer — Nashville, Tennessee
- Improving Utilization of Lung Cancer Screening in Underserved PA Populations — Allentown, Pennsylvania
- Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting — Houston, Texas
- Testing the Engaged Approach to Lung Cancer Screening — Denver, Colorado
- Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer — Boston, Massachusetts
Explore by condition: All Lung Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.