๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-03-16

Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery (NCT01570998)

Targeted Intraoperative Radiotherapy United States (TARGIT-US) Phase IV Registry Trial: A Registry Trial of Targeted Intraoperative Radiation Therapy Following Breast-conserving Surgery

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: University of California, San Francisco

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase IV trial studies the side effects of intraoperative radiation therapy and how well it works in treating patients with breast cancer undergoing breast-conserving surgery. Delivering radiation one time to the area where the tumor was removed while the patient is still in the operating room may kill any residual tumor cells and may be as effective as standard radiation therapy in patients with early stage breast cancer.

Who can join: Review the eligibility criteria below.

Location: Alta Bates Summit Medical Center-Herrick Campus โ€” Berkeley, California

Age range: 45 Years

๐Ÿงช Interventions in This Study

  • Intraoperative Radiation Therapy (RADIATION)
  • Laboratory Biomarker Analysis (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (25 Sites)

  • Alta Bates Summit Medical Center-Herrick Campus โ€” Berkeley, California
  • University of California, Irvine โ€” Irvine, California
  • Dignity Health - California Hospital Medical Center โ€” Los Angeles, California
  • University of California, San Francisco โ€” San Francisco, California
  • John Muir Medical Center-Walnut Creek โ€” Walnut Creek, California
  • Greenwich Hospital โ€” Greenwich, Connecticut
  • MedStar Georgetown University Hospital โ€” Washington D.C., District of Columbia
  • MedStar Washington Hospital Center โ€” Washington D.C., District of Columbia
  • Cleveland Clinic โ€” Fort Lauderdale, Florida
  • Holy Cross Hospital โ€” Fort Lauderdale, Florida
  • Memorial Health University Medical Center โ€” Savannah, Georgia
  • Northwestern University โ€” Chicago, Illinois
  • Loyola University Medical Center โ€” Maywood, Illinois
  • Community Cancer Center South โ€” Indianapolis, Indiana
  • Mercy Medical Center โ€” Baltimore, Maryland
  • Lahey Hospital and Medical Center โ€” Burlington, Massachusetts
  • Marie Yeager Cancer Center, Spectrum Health Lakeland โ€” Saint Joseph, Michigan
  • Community Hospital at Dobbs Ferry โ€” Dobbs Ferry, New York
  • Cornell University โ€” Ithaca, New York
  • Columbia University/Herbert Irving Cancer Center โ€” New York, New York
  • Vassar Brothers Medical Center โ€” Poughkeepsie, New York
  • Saint Luke's Hospital-Anderson Campus โ€” Easton, Pennsylvania
  • Inova Fairfax Hospital Cancer Center โ€” Fairfax, Virginia
  • Sentara Port Warwick โ€” Newport News, Virginia
  • Aurora BayCare Medical Center โ€” Green Bay, Wisconsin

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—