Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort (NCT01574053)
🩺 Plain-English Summary (8th-Grade Level)
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and biomarkers for progression and prognosis, identifying clinically-relevant phenotypic characteristics, and establishing clearly defined endpoints for interventional studies. Periodic cuts of the database are now available to any interested researcher to use in their research - visit www.enroll-hd.org/for-researchers/access-data/ to learn more.
Who can join: Review the eligibility criteria below.
Location: University of Alabama — Birmingham, Alabama
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (183 Sites)
Showing the first 25 of 183 sites.
- University of Alabama — Birmingham, Alabama
- St. Joseph's Hospital and Medical Center — Phoenix, Arizona
- University of California - Irvine Medical Center — Irvine, California
- Loma Linda Medical Center — Loma Linda, California
- University of California - Los Angeles — Los Angeles, California
- University of California - Davis — Sacramento, California
- University of California - San Diego — San Diego, California
- University of California - San Francisco — San Francisco, California
- Cenexel Rocky Mountain Clinical Research, LLC — Englewood, Colorado
- University of Connecticut — Farmington, Connecticut
- Georgetown University — Washington D.C., District of Columbia
- University of Florida Board of Trustees — Gainesville, Florida
- University of Miami — Miami, Florida
- University of South Florida, HDSA Center of Excellence at USF — Tampa, Florida
- Emory University, Wesley Woods Health Center — Atlanta, Georgia
- Georgia Health Sciences University — Augusta, Georgia
- Northwestern University — Chicago, Illinois
- University of Chicago — Chicago, Illinois
- Rush University Medical Center — Chicago, Illinois
- University of Illinois College of Medicine at Rockford — Rockford, Illinois
- Indiana University — Indianapolis, Indiana
- University of Iowa — Iowa City, Iowa
- University of Kansas Medical Center — Kansas City, Kansas
- Hereditary Neurological Disease Center — Wichita, Kansas
- University of Louisville — Louisville, Kentucky
📞 Contact the Study Coordinator
Phone: (205) 996-2807
Email: jltidwell@uabmc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Huntington's Disease
- Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manifest Huntington's Disease — Birmingham, Alabama
- HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease — Englewood, Colorado
- A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease — Edmonton,
Explore by condition: All Huntington's Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.