🏛️ Verified NIH Record • Updated 2026-05-22

COsegregation of VARiants in Panel of Genes (NCT01689584)

Study of Family COsegregation of Nucleotide VARiants in the Panel of Genes to Validate Their Use in Genetic Counseling

🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Institut Curie

🩺 Plain-English Summary (8th-Grade Level)

The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic surgery.

Who can join: Review the eligibility criteria below.

Location: Centre Hospitalier de Bastia — Bastia, Corsica

Age range: 18 Years

🧪 Interventions in This Study

  • salivary kit (GENETIC)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (62 Sites)

Showing the first 25 of 62 sites.

  • Centre Hospitalier de Bastia — Bastia, Corsica
  • Institut Curie - Saint-Cloud site — Saint-Cloud, Haut de Seine
  • CHU Amiens - Hôpital Nord — Amiens,
  • ICO - Centre Paul Papin — Angers,
  • Centre Hospitalier d'Angoulème — Angoulême,
  • Institut Sainte-Catherine — Avignon,
  • CHU Besançon — Besançon,
  • Groupe Hospitalier Pellegrin — Bordeaux,
  • Institut Bergonié — Bordeaux,
  • Centre Hospitalier Jacques Coeur — Bourges,
  • CHU Morvan de Brest — Brest,
  • Centre François Baclesse — Caen,
  • Centre Hospitalier Hôtel Dieu — Chambéry,
  • Centre Jean Perrin — Clermont-Ferrand,
  • Hôpital Civil de Colmar — Colmar,
  • CHU de Dijon — Dijon,
  • CHU de Grenoble — Grenoble,
  • CHD Vendée — La Roche-sur-Yon,
  • Groupe Hospitalier La Rochelle-Ré-Aunis — La Rochelle,
  • Hôpital Flaubert — Le Havre,
  • Centre Oscar Lambret — Lille,
  • Chru Lille — Lille,
  • CHU Dupuytren — Limoges,
  • Hospices Civils de Lyon — Lyon,
  • Centre Léon Bérard — Lyon,

📞 Contact the Study Coordinator

Phone: 33172389367

Email: sandrine.caputo@curie.fr

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗