Atypical Fracture Cohort Study (NCT01747291)
Atypical Femur Fracture Ontario Cohort Registry
🩺 Plain-English Summary (8th-Grade Level)
Osteoporosis is a disease characterized by increased bone fragility and deteriorating bone micro-architecture. The main consequence of osteoporosis is low-trauma fractures, most often of the hip, spine and wrist. Recently, another type of low-trauma fracture, atypical femur fractures (AFFs), have received much attention. Little is known of the cause of these debilitating fractures; however, they have been associated with long term bisphosphonate use. What we currently know about AFFs is based on case reports or small case series, or studies using administrative databases or secondary analyses of bisphosphonate trials. While these reports provide some preliminary information on the relationship between long term bisphosphonate exposure and AFFs, detailed clinical data are absent. As we have established a network of specialists across southern Ontario our group is in a position to collect meaningful information on a larger group of patients who have experienced these debilitating fractures into a centralized AFF registry.
Who can join: Review the eligibility criteria below.
Location: McMaster University — Hamilton, Ontario
Age range: 20 Years to 100 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- McMaster University — Hamilton, Ontario
- University Health Network — Toronto, Ontario
- St Michael's Hospital — Toronto, Ontario
📞 Contact the Study Coordinator
Phone: (416) 340-4841
Email: jscher@uhnresearch.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atypical Femur Fracture
- Evaluation of IVA (SE Femur Scans) to Identify Incomplete AFFs — Toronto, Ontario
- Personalizing Osteoporosis Care: Clinical & Genetic Risk Factors for AFFs — Hamilton, Ontario
- Quebec Registry for Atypical Femur Fractures — Montreal, Quebec
Explore by condition: All Atypical Femur Fracture clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.