๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-09

Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma (NCT01849263)

Phase 2 Trial of Single-Agent Ibrutinib (PCI-32765) in Relapsed or Refractory Follicular Lymphoma

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase II trial studies how well ibrutinib works in treating patients with follicular lymphoma that has come back after a period of improvement or does not respond to treatment. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Who can join: Review the eligibility criteria below.

Location: Mayo Clinic in Arizona โ€” Scottsdale, Arizona

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (13 Sites)

  • Mayo Clinic in Arizona โ€” Scottsdale, Arizona
  • Mayo Clinic in Florida โ€” Jacksonville, Florida
  • Mayo Clinic in Rochester โ€” Rochester, Minnesota
  • Metro Minnesota Community Oncology Research Consortium โ€” Saint Louis Park, Minnesota
  • Park Nicollet Clinic - Saint Louis Park โ€” Saint Louis Park, Minnesota
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Fox Chase Cancer Center โ€” Philadelphia, Pennsylvania
  • University of Wisconsin Carbone Cancer Center - University Hospital โ€” Madison, Wisconsin
  • Juravinski Cancer Centre at Hamilton Health Sciences โ€” Hamilton, Ontario
  • Kingston Health Sciences Centre โ€” Kingston, Ontario
  • University Health Network-Princess Margaret Hospital โ€” Toronto, Ontario
  • National University Hospital Singapore โ€” Singapore,
  • National Cancer Centre Singapore โ€” Singapore,

๐Ÿ“ž Contact the Study Coordinator

Phone: (800) 664-4580

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Grade 3a Follicular Lymphoma

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—