Cervical Spondylotic Myelopathy Surgical Trial (NCT02076113)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of the study is to determine the optimal surgical approach (ventral vs dorsal) for patients with multi-level cervical spondylotic myelopathy (CSM). There are no established guidelines for the management of patients with CSM, which represents the most common cause of spinal cord injury and dysfunction in the US and in the world. This study aims to test the hypothesis that ventral surgery is associated with superior Short Form-36 physical component Score (SF-36 PCS) outcome at one year follow-up compared to dorsal approaches and that both ventral and dorsal surgery improve symptoms of spinal cord dysfunction measured using the modified Japanese Orthopedic Association Score (mJOA). A secondary hypothesis is that health resource utilization for ventral surgery, dorsal fusion, and laminoplasty surgery are different. A third hypothesis is that cervical sagittal balance post-operatively is a significant predictor of SF-36 PCS outcome.
Who can join: Review the eligibility criteria below.
Location: University of California- San Francisco — San Francisco, California
Age range: 45 Years to 80 Years
🧪 Interventions in This Study
- Ventral (Front) decompression with Fusion (PROCEDURE)
- Dorsal (Back) Decompression with Fusion (PROCEDURE)
- Dorsal (back) Laminoplasty (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- University of California- San Francisco — San Francisco, California
- Emory — Atlanta, Georgia
- University of Kansas Medical Center — Kansas City, Kansas
- Lahey Hospital and Medical Center — Burlington, Massachusetts
- Washington University School of Medicine- St. Louis — St Louis, Missouri
- Rutgers-New Jersey Medical School — Newark, New Jersey
- Hospital for Special Surgery — New York, New York
- Columbia — New York, New York
- Cleveland Clinic Foundation — Cleveland, Ohio
- MetroHealth — Cleveland, Ohio
- Thomas Jefferson University Hospital — Philadelphia, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- University of Utah Health Sciences — Salt Lake City, Utah
- University of Wisconsin — Madison, Wisconsin
- Medical College of Wisconsin — Milwaukee, Wisconsin
- University Health Network-University of Toronto — Toronto, Ontario
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cervical Spondylosis With Myelopathy
- Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty — Los Angeles, California
Explore by condition: All Cervical Spondylosis With Myelopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.