๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-21

Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma (NCT02176967)

Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients With Non-High-Risk Neuroblastoma

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Children's Oncology Group

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma. Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Measuring biomarkers in tumor cells may help plan when effective treatment is necessary and what the best treatment is. Response and biology-based risk factor-guided therapy may be effective in treating patients with non-high risk neuroblastoma and may help to avoid some of the risks and side effects related to standard treatment.

Who can join: Review the eligibility criteria below.

Location: Children's Hospital of Alabama โ€” Birmingham, Alabama

Age range: Not specified to 18 Months

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (222 Sites)

Showing the first 25 of 222 sites.

  • Children's Hospital of Alabama โ€” Birmingham, Alabama
  • USA Health Strada Patient Care Center โ€” Mobile, Alabama
  • Providence Alaska Medical Center โ€” Anchorage, Alaska
  • Banner Children's at Desert โ€” Mesa, Arizona
  • Phoenix Childrens Hospital โ€” Phoenix, Arizona
  • Banner University Medical Center - Tucson โ€” Tucson, Arizona
  • Arkansas Children's Hospital โ€” Little Rock, Arkansas
  • Kaiser Permanente Downey Medical Center โ€” Downey, California
  • City of Hope Comprehensive Cancer Center โ€” Duarte, California
  • Loma Linda University Medical Center โ€” Loma Linda, California
  • Miller Children's and Women's Hospital Long Beach โ€” Long Beach, California
  • Children's Hospital Los Angeles โ€” Los Angeles, California
  • Cedars-Sinai Medical Center โ€” Los Angeles, California
  • Valley Children's Hospital โ€” Madera, California
  • UCSF Benioff Children's Hospital Oakland โ€” Oakland, California
  • Kaiser Permanente-Oakland โ€” Oakland, California
  • Children's Hospital of Orange County โ€” Orange, California
  • Lucile Packard Children's Hospital Stanford University โ€” Palo Alto, California
  • Sutter Medical Center Sacramento โ€” Sacramento, California
  • University of California Davis Comprehensive Cancer Center โ€” Sacramento, California
  • Rady Children's Hospital - San Diego โ€” San Diego, California
  • Naval Medical Center -San Diego โ€” San Diego, California
  • UCSF Medical Center-Mission Bay โ€” San Francisco, California
  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center โ€” Torrance, California
  • Children's Hospital Colorado โ€” Aurora, Colorado

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—