Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma (NCT02180711)
An Open-label, Phase 1b/2 Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma
๐ฉบ Plain-English Summary (8th-Grade Level)
Part 1: To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with R/R FL. Part 2: To characterize the activity of acalabrutinib alone or in combination with rituximab in subjects with R/R MZL, as measured by ORR. Part 3: To characterize the safety of acalabrutinib in combination with rituximab and lenalidomide in subjects with R/R FL
Who can join: Review the eligibility criteria below.
Location: Research Site โ Tucson, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (29 Sites)
Showing the first 25 of 29 sites.
- Research Site โ Tucson, Arizona
- Research Site โ Downey, California
- Research Site โ Duarte, California
- Research Site โ Fountain Valley, California
- Research Site โ Santa Monica, California
- Research Site โ Coral Gables FL, Florida
- Research Site โ Chicago, Illinois
- Research Site โ Chicago, Illinois
- Research Site โ Chicago, Illinois
- Research Site โ Louisville, Kentucky
- Research Site โ New Orleans, Louisiana
- Research Site โ Ann Arbor, Michigan
- Research Site โ Morristown, New Jersey
- Research Site โ Lake Success, New York
- Research Site โ New York, New York
- Research Site โ Columbus, Ohio
- Research Site โ Greenville, South Carolina
- Research Site โ Dallas, Texas
- Research Site โ Houston, Texas
- Research Site โ San Antonio, Texas
- Research Site โ Temple, Texas
- Research Site โ Salt Lake City, Utah
- Research Site โ Spokane, Washington
- Research Site โ Edmonton, Alberta
- Research Site โ London, Ontario
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Non Hodgkin Lymphoma
- Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT) โ Duarte, California
- TmCD19-IL18 in CD19+ Cancers โ Philadelphia, Pennsylvania
- Intrathecal Rituximab With Standard Intrathecal Prophylaxis to Prevent CNS Relapse for CD 20+ Non Hodgkin Lymphoma โ Cincinnati, Ohio
- Evaluate the Safety of UF-KURE19 Cells in Non-Hodgkin Lymphomas โ Iowa City, Iowa
- Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies โ Cleveland, Ohio
Explore by condition: All Non Hodgkin Lymphoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.