Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts (NCT02181257)
Extracorporeal Photopheresis for the Management of Progressive Bronchiolitis Obliterans Syndrome in Medicare-Eligible Recipients of Lung Allografts
🩺 Plain-English Summary (8th-Grade Level)
The primary aims of this study is to determine the efficacy and tolerability of Extracorporeal Photopheresis (ECP) for the treatment of either Refractory Bronchiolitis Obliterans Syndrome (BOS) patients (258 at cessation of enrollment April 7, 2022) or Newly Diagnosed (22 as of enrollment Hold February 2022) Bronchiolitis Obliterans Syndrome patients after lung transplantation. In compliance with the Centers for Medicare and Medicaid Services' (CMS) Coverage with Evidence Development (CED) decision, the study will collect specified demographic, comorbidity, treatment, and outcome data exclusively for Medicare beneficiaries who are treated with ECP for either refractory or New BOS.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (22 Sites)
- University of Alabama at Birmingham — Birmingham, Alabama
- St. Joseph's Hospital and Medical Center — Phoenix, Arizona
- University of California San Diego — La Jolla, California
- University of Florida — Gainsville, Florida
- Northwestern University — Chicago, Illinois
- Indiana University Health — Indianapolis, Indiana
- University of Iowa — Iowa City, Iowa
- University of Kentucky — Lexington, Kentucky
- Brigham and Women's Hospital — Boston, Massachusetts
- University of Michigan Health System — Ann Arbor, Michigan
- Spectrum Health — Grand Rapids, Michigan
- University of Minnesota Medical Center, Fairview — Minneapolis, Minnesota
- Washington University School of Medicine — St Louis, Missouri
- Columbia University — New York, New York
- Duke University — Durham, North Carolina
- Ohio State University — Columbus, Ohio
- Temple University — Philadelphia, Pennsylvania
- University of Pittsburgh — Pittsburgh, Pennsylvania
- Baylor University Medical Center — Dallas, Texas
- UT Southwestern Medical Center — Dallas, Texas
- Houston Methodist — Houston, Texas
- Inova Health System — Falls Church, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Bronchiolitis Obliterans Syndrome (BOS) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.