Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis (NCT02315729)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on child health, the etiology of AIS and molecular mechanisms underlying its development and progression remain poorly understood. Clinical criteria and features cannot adequately predict which children, diagnosed with mild disease, will undergo subsequent curve progression requiring intervention. The investigators hypothesize that alterations in specific genetic markers will be correlated with the progression of AIS curves over time. Thus, these markers could be used in the future to develop a reliable, inexpensive and relatively non-invasive cell based diagnostic test to (1) predict spinal curve progression in AIS, (2) select patients likely to benefit from early surgical intervention, and (3) potentially screen for asymptomatic children at risk of developing idiopathic scoliosis.
Who can join: Review the eligibility criteria below.
Location: Children'S Hospital of Colorado — Denver, Colorado
Age range: 10 Years to 13 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Children'S Hospital of Colorado — Denver, Colorado
📞 Contact the Study Coordinator
Phone: (303) 724-7457
Email: jiandong.hao@cuanschutz.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Adolescent Idiopathic Scoliosis
- Effect of a Postural Re-education Intervention Compared to Standard Care on Scoliosis Progression in Adolescent — Montreal, Quebec
- 3D Body Surface Modeling for Scoliosis Monitoring — Palo Alto, California
- Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS) — San Diego, California
- Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis — Baltimore, Maryland
- Kids With Iron Deficiency and Scoliosis — New York, New York
Explore by condition: All Adolescent Idiopathic Scoliosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.