OCT Biomarkers for Diabetic Retinopathy (NCT02330042)
Functional Optical Coherence Tomography-Derived Biomarkers for Diabetic Retinopathy
🩺 Plain-English Summary (8th-Grade Level)
Diabetic retinopathy (DR) is caused by changes in the blood vessels of the retina associated with long-term Type 1 or Type 2 diabetes mellitus. DR is a leading cause of blindness in the United States. Standard optical coherence tomography (OCT) cannot directly detect vascular changes, which may occur early affecting the passage of blood through the tiny capillaries (reduced capillary flow) or cause the greatest damage through formation of abnormal blood vessel growth (neovascularization). Currently, fluorescein angiography (FA) is the gold standard for detecting these changes, but FA requires an injection of a dye into the vein of the arm of the patient. This dye can cause undesirable side effects. Recently, OCT has been used to make functional measurements (such as total retinal blood flow among others) and to perform angiography. Thus, functional OCT may provide a useful, alternate way to evaluate diabetic retinopathy.
Who can join: Review the eligibility criteria below.
Location: Oregon Health & Science University — Portland, Oregon
Age range: 18 Years to 79 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Oregon Health & Science University — Portland, Oregon
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Diabetic Retinopathy
- Vascular Reparative Mechanism in Diabetes — Birmingham, Alabama
- WF and PR OCTA in Diabetic Retinopathy — Portland, Oregon
- Camera Qualification Study — Norco, California
- A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy — Phoenix, Arizona
- Implementation of Teleophthalmology in Urban Health Systems Study — Madison, Wisconsin
Explore by condition: All Diabetic Retinopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.