Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients (NCT02338947)
A Multicenter, Prospective, Randomized, Clinical Trial Comparing Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients
🩺 Plain-English Summary (8th-Grade Level)
Frailty is defined as a geriatric syndrome of impaired resiliency to stressors (such as cardiac surgery) that has been delineated recently in the cardiovascular literature. One of the most controversial areas of cardiac surgery has been whether off-pump coronary artery bypass grafting (OPCAB) surgery is superior to conventional on-pump coronary artery bypass grafting (CABG) surgery. There is an ongoing debate about the benefits and disadvantages of OPCAB surgery and we believe that this remains an important technique for the improvement of coronary surgery. The benefits of CABG surgery in frail patients are still undetermined. The aim of this study is to clarify the potential benefit of OPCAB surgery in pre-frail and frail patients by comparing off-pump versus on-pump CABG in these patients.
Who can join: Review the eligibility criteria below.
Location: Emory University School of Medicine — Atlanta, Georgia
Age range: 60 Years
🧪 Interventions in This Study
- Off-pump coronary-artery bypass grafting (OTHER)
- On-pump coronary-artery bypass grafting (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (7 Sites)
- Emory University School of Medicine — Atlanta, Georgia
- Hospital de Messejana — Fortaleza, Ceará
- Hospital das Clínicas Samuel Libânio — Pouso Alegre, Minas Gerais
- Hospital Alberto Urquiza Wanderley — João Pessoa, Paraíba
- Instituto Nacional de Cardiologia de Laranjeiras — Rio de Janeiro, Rio de Janeiro
- Beneficência Portuguesa de São Paulo — São Paulo, São Paulo
- Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina de São Paulo — São Paulo, São Paulo
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Frail Elderly
- Targeting Aging With a Ketone Ester for Function in Frailty — Novato, California
- Comparison of Smartphone and Community-Based Delivery of the Otago Exercise Program for Fall Risk in Older Adults — Binghamton, New York
Explore by condition: All Frail Elderly clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.