๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-02-03

Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer (NCT02446405)

Randomised Phase 3 Trial of Enzalutamide in First Line Androgen Deprivation Therapy for Metastatic Prostate Cancer: ENZAMET

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: University of Sydney

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to determine the effectiveness of enzalutamide, versus a conventional non-steroidal anti androgen (NSAA), when combined with a luteinizing hormone releasing hormone analog (LHRHA) or surgical castration, as first line androgen deprivation therapy (ADT) for newly diagnosed metastatic prostate cancer.

Who can join: Review the eligibility criteria below.

Location: Dana Farber Cancer Institute โ€” Boston, Massachusetts

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (82 Sites)

Showing the first 25 of 82 sites.

  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Chris O'Brien Lifehouse โ€” Camperdown, New South Wales
  • Coffs Harbour Health Campus โ€” Coffs Harbour, New South Wales
  • Concord Cancer Centre - Concord Repatriation General Hospital โ€” Concord, New South Wales
  • St Vincent's Hospital Sydney โ€” Darlinghurst, New South Wales
  • Nepean Cancer Care Centre โ€” Kingswood, New South Wales
  • St. George Hospital โ€” Kogarah, New South Wales
  • Central West Cancer Services โ€” Orange, New South Wales
  • Port Macquarie Base Hospital โ€” Port Macquarie, New South Wales
  • Prince of Wales Hospital โ€” Randwick, New South Wales
  • Genesis Care North Shore โ€” St Leonards, New South Wales
  • Tamworth Rural Referral Hospital โ€” Tamworth, New South Wales
  • The Tweed Hospital โ€” Tweed Heads, New South Wales
  • Riverina Cancer Care Centre โ€” Wagga Wagga, New South Wales
  • Sydney Adventist Hospital โ€” Wahroonga, New South Wales
  • Wollongong Hospital โ€” Wollongong, New South Wales
  • Royal Darwin Hospital โ€” Tiwi, Northern Territory
  • Sunshine Coast University Hospital โ€” Birtinya, Queensland
  • Townsville Hospital โ€” Douglas, Queensland
  • Royal Brisbane and Women's Hospital โ€” Herston, Queensland
  • Gold Coast University Hospital โ€” Southport, Queensland
  • Princess Alexandra Hospital โ€” Woolloongabba, Queensland
  • Royal Adelaide Hospital โ€” Adelaide, South Australia
  • Flinders Medical Centre โ€” Bedford Park, South Australia
  • Adelaide Cancer Centre - Ashford Cancer Care Centre โ€” Kurralta Park, South Australia

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—