๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-04

Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer (NCT02446444)

Randomised Phase 3 Trial of Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer: ENZARAD

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: University of Sydney

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to determine the effectiveness of enzalutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinizing hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate cancer at high risk of recurrence.

Who can join: Review the eligibility criteria below.

Location: Dana Farber Cancer Institute โ€” Boston, Massachusetts

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (69 Sites)

Showing the first 25 of 69 sites.

  • Dana Farber Cancer Institute โ€” Boston, Massachusetts
  • Beth Israel Deaconess Medical Center โ€” Boston, Massachusetts
  • Blacktown Hospital โ€” Blacktown, New South Wales
  • Campbelltown Hospital โ€” Campbelltown, New South Wales
  • Chris O'Brien Lifehouse โ€” Camperdown, New South Wales
  • Genesis Cancer Care Newcastle โ€” Gateshead, New South Wales
  • Gosford Hospital โ€” Gosford, New South Wales
  • St George Hospital โ€” Kogarah, New South Wales
  • Liverpool Hospital โ€” Liverpool, New South Wales
  • Orange Health Service โ€” Orange, New South Wales
  • Prince of Wales Hospital โ€” Randwick, New South Wales
  • Royal North Shore Hospital โ€” St Leonards, New South Wales
  • St Vincent's Hospital โ€” Sydney, New South Wales
  • Tamworth Rural Referral Hospital โ€” Tamworth, New South Wales
  • Sydney Adventist Hospital โ€” Wahroonga, New South Wales
  • Calvary Mater Newcastle โ€” Waratah, New South Wales
  • Westmead Hospital โ€” Westmead, New South Wales
  • Wollongong Hospital โ€” Wollongong, New South Wales
  • Genesis Cancer Care Queensland - Wesley and Chermside โ€” Auchenflower, Queensland
  • Townsville Hospital โ€” Douglas, Queensland
  • Royal Brisbane & Womens Hospital โ€” Herston, Queensland
  • Nambour General Hospital โ€” Nambour, Queensland
  • Radiation Oncology Services Mater Centre โ€” South Brisbane, Queensland
  • ICON - Gold Coast (formerly ROC Gold Coast) โ€” Southport, Queensland
  • ICON - Toowoomba (formerly ROC Toowoomba) โ€” Toowoomba, Queensland

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—