A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma (NCT02455245)
A Phase III Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma
🩺 Plain-English Summary (8th-Grade Level)
This study is trying to learn and understand if the chemotherapy drug called carboplatin works as well as the standard therapy. The standard therapy for Low Grade Glioma (LGG) in children and young adults is using a combination of carboplatin and vincristine. Studies in children have shown that the use of carboplatin alone has promise of being just as effective for treating LGG as standard therapy. Additionally, this study will try to understand if treatment with carboplatin alone is associated with an improved quality of life for LGG patients and their families.
Who can join: Review the eligibility criteria below.
Location: Phoenix Children's Hospital — Phoenix, Arizona
Age range: Not specified to 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Phoenix Children's Hospital — Phoenix, Arizona
- Rady Children's Hospital — San Diego, California
- Yale University — New Haven, Connecticut
- Orlando Health, Inc. — Orlando, Florida
- Ann & Robert H. Lurie Children's Hosptial of Chicago — Chicago, Illinois
- St. Vincent Peyton Manning Children's Hospital — Indianapolis, Indiana
- University of Iowa — Iowa City, Iowa
- The Johns Hopkins Hospital — Baltimore, Maryland
- Dana-Farber Cancer Institute — Boston, Massachusetts
- University of Michigan, C.S. Mott Children's Hospital — Ann Arbor, Michigan
- Children's Hospitals and Clinics of Minnesota - Minneapolis — Minneapolis, Minnesota
- Saint Louis University at SSM Cardinal Glennon Children's Medical Center — St Louis, Missouri
- Washington University School of Medicine — St Louis, Missouri
- Albany Medical Center — Albany, New York
- Duke University Medical School — Durham, North Carolina
- Children's Hospital Medical Center of Akron — Akron, Ohio
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio
- Nationwide Children's Hospital — Columbus, Ohio
- Dayton Children's Hospital — Dayton, Ohio
- American Family Children's Hospital — Madison, Wisconsin
- Medical College of Wiscosin — Milwaukee, Wisconsin
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Low Grade Glioma
- Vinblastine +/- Bevacizumab in Children With Unresectable or Progressive Low Grade Glioma (LGG) — Los Angeles, California
- Proton Radiation Therapy for Gliomas — Boston, Massachusetts
- Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma — Los Angeles, California
- A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma — Birmingham, Alabama
- Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma — Detroit, Michigan
Explore by condition: All Low Grade Glioma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.