PALbociclib CoLlaborative Adjuvant Study (NCT02513394)
PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer
🩺 Plain-English Summary (8th-Grade Level)
This is a prospective, two arm, international, multicenter, randomized, open-label Phase III study evaluating the addition of 2 years of palbociclib to standard adjuvant endocrine therapy for patients with HR+ / HER2- early breast cancer (EBC). The purpose of the PALLAS study is to determine whether the addition of palbociclib to adjuvant endocrine therapy will improve outcomes over endocrine therapy alone for HR+/HER2- early breast cancer. Assessment of a variety of correlative analysis, including evaluation of the effect of palbociclib in genomically defined tumor subgroups, is planned.
Who can join: Review the eligibility criteria below.
Location: University of South Alabama Mitchell Cancer Institute — Mobile, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (437 Sites)
Showing the first 25 of 437 sites.
- University of South Alabama Mitchell Cancer Institute — Mobile, Alabama
- Southern Cancer Center PC - Providence — Mobile, Alabama
- Katmai Oncology Group — Anchorage, Alaska
- Providence Alaska Cancer Center — Anchorage, Alaska
- Mayo Clinic in Arizona — Phoenix, Arizona
- Kaiser Permanente Anaheim Medical Center — Anaheim, California
- Kaiser Permanente Baldwin Park Medical Center — Baldwin Park, California
- Kaiser Permanente Bellflower Medical Center — Bellflower, California
- Kaiser Permanente Fontana Medical Center — Fontana, California
- Marin Cancer Care — Greenbrae, California
- Marin Cancer Center — Greenbrae, California
- Kaiser Permanente Harbor City Medical Center — Harbor City, California
- Kaiser Permanente Irvine Medical Center — Irvine, California
- UCSD Moores Cancer Center — La Jolla, California
- Long Beach Memorial Medical Center - Todd Cancer Institute — Long Beach, California
- Kaiser Permanente Sunset Medical Center — Los Angeles, California
- Cedars Sinai Medical Center — Los Angeles, California
- Kaiser Permanente Oakland Medical Center — Oakland, California
- Palo Alto Medical Foundation Health Care — Palo Alto, California
- Kaiser Permanente Panorama City Medical Center — Panorama City, California
- Kaiser Permanente Riverside Medical Center — Riverside, California
- Kaiser Permanente Roseville Medical Center — Roseville, California
- Kaiser Permanente Sacramento Medical Center — Sacramento, California
- University of California — San Diego, California
- Kaiser Permanente San Diego Medical Center — San Diego, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.