๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-16

Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation (NCT02521285)

Effect of Aspirin on Biomarkers of Barrett's Esophagus After Successful Eradication of Barrett's Esophagus With Radiofrequency Ablation

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This randomized phase II trial studies the safety of and how well aspirin works in preventing Barrett's esophagus from returning after it has been successfully eliminated by radiofrequency ablation. Studying samples of tissue from patients with Barrett's esophagus for the levels of a specific protein that is linked to developing Barrett's esophagus may help doctors learn whether aspirin can prevent it from returning after it has been successfully treated.

Who can join: Review the eligibility criteria below.

Location: UCLA / Jonsson Comprehensive Cancer Center โ€” Los Angeles, California

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (10 Sites)

  • UCLA / Jonsson Comprehensive Cancer Center โ€” Los Angeles, California
  • UCHealth University of Colorado Hospital โ€” Aurora, Colorado
  • Northwestern University โ€” Chicago, Illinois
  • Mayo Clinic in Rochester โ€” Rochester, Minnesota
  • Kansas City Veterans Affairs Medical Center โ€” Kansas City, Missouri
  • UNC Lineberger Comprehensive Cancer Center โ€” Chapel Hill, North Carolina
  • University of Pennsylvania/Abramson Cancer Center โ€” Philadelphia, Pennsylvania
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center โ€” Houston, Texas
  • UT MD Anderson Cancer Center โ€” Houston, Texas
  • Saint Michael's Hospital โ€” Toronto, Ontario

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—