OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages (NCT02523118)
A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients With Eosinophilic Esophagitis (EoE), Gastritis (EoG), Enteritis (EoN) and Colitis (EoC)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this observational study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, EoN and EoC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look. We are aiming to compare different tissue components such as inflammatory cell types with clinical symptoms. We want to see if scores on standard questionnaires can give us an idea how well the person is doing.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic Hospital — Phoenix, Arizona
Age range: 3 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (19 Sites)
- Mayo Clinic Hospital — Phoenix, Arizona
- Arkansas Children's Research Institute — Rogers, Arkansas
- Rady Children's Hospital — San Diego, California
- University of Colorado Denver — Aurora, Colorado
- Children's Hospital Colorado — Denver, Colorado
- Northwestern University — Chicago, Illinois
- Ann and Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois
- Riley Children's Hospital — Indianapolis, Indiana
- National Institutes of Health (NIH) — Bethesda, Maryland
- Tufts University — Boston, Massachusetts
- Mayo Clinic — Rochester, Minnesota
- Icahn School of Medicine at Mount Sinai — New York, New York
- University of North Carolina, Chapel Hill — Chapel Hill, North Carolina
- Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania
- University of Pennsylvania — Philadelphia, Pennsylvania
- Vanderbilt University Medical Center — Nashville, Tennessee
- Baylor College of Medicine & Texas Children's Hospital — Houston, Texas
- University of Utah — Salt Lake City, Utah
📞 Contact the Study Coordinator
Phone: (513) 636-7832
Email: bliss.magella@cchmc.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Eosinophilic Gastrointestinal Disorders (EGIDs) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.