Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors (NCT02574728)

🧪 Interventions in This Study

• Sirolimus (DRUG)
• Celecoxib (DRUG)
• Etoposide (DRUG)
• Cyclophosphamide (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (6 Sites)

• Phoenix Children's Hospital — Phoenix, Arizona
• Nemours/Alfred I. duPont Hospital for Children — Wilmington, Delaware
• Children's Healthcare of Atlanta-Egleston — Atlanta, Georgia
• Children's Healthcare of Atlanta, Scottish Rite — Atlanta, Georgia
• Children's Mercy Hospital — Kansas City, Missouri
• University of Virginia Health System — Charlottesville, Virginia

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.