🏛️ Verified NIH Record • Updated 2026-02-04
Tocotrienol Against the Progression of End Stage Liver Disease (NCT02581085)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Chandan Sen
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this Phase 2 trial is to validate the outcome observed in a previous trial that oral Tocotrienol (TCT) attenuates the rise in MELD score over time in patients with end stage liver disease / cirrhosis. The study is double blind and participants will be randomized to take 2 capsules of TCT (200mg) or placebo twice a day for 3 years.
Who can join: Review the eligibility criteria below.
Location: IU Health Unviersity Hospital — Indianapolis, Indiana
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- IU Health Unviersity Hospital — Indianapolis, Indiana
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in End Stage Liver Disease
- Disparities Among Liver Transplant Patients — Phoenix, Arizona
- Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes — Boston, Massachusetts
- Adverse Outcomes and Mortality in Liver Transplant — Phoenix, Arizona
- Functional Assessment in Liver Transplantation — Little Rock, Arkansas
Explore by condition: All End Stage Liver Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.