Aging, Geriatric Syndromes and Clonal Hematopoiesis (NCT02604563)
🩺 Plain-English Summary (8th-Grade Level)
In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.
Who can join: Review the eligibility criteria below.
Location: Washington University School of Medicine — St Louis, Missouri
Age range: 50 Years
🧪 Interventions in This Study
- Cognitive Assessment (OTHER)
- Activities of Daily Living Questionnaire (OTHER)
- Instrumental Activities of Daily Living, subscale of the OARS (OTHER)
- Karnofsky Self-reported Performance Rating Scale (OTHER)
- Number of Falls (OTHER)
- Physical Health Section, subscale of the OARS (OTHER)
- MOS Social Activity Survey (OTHER)
- Unintentional Weight Loss (OTHER)
- Peripheral Blood Draw (GENETIC)
- Buccal Swab (GENETIC)
- Heart Health and Smoking History from BRFSS questionnaire (OTHER)
- Gait Speed (OTHER)
- Grip Strength (OTHER)
- Height and Weight measurements (OTHER)
- Blood pressure measurement (OTHER)
- Optional bone marrow biopsy (PROCEDURE)
- Blood draw for trauma measurements (PROCEDURE)
- Femur head donation (OTHER)
- Knee bone fragments (OTHER)
- Bone marrow aspirate (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Washington University School of Medicine — St Louis, Missouri
📞 Contact the Study Coordinator
Phone: (314) 747-8439
Email: mjacoby@wustl.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Geriatrics
- Social Deprivation Assessment in Older Adults — Montreal, Quebec
- Geriatrics in the Intensive Care Unit — Villavicencio, Meta Department
Explore by condition: All Geriatrics clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.