🏛️ Verified NIH Record • Updated 2026-03-16
An Open Label Study of CM-AT for the Treatment of Children With Autism (NCT02649959)
An Open-Label Extension Study of CM-AT for the Treatment of Children With Autism With All Levels of Fecal Chymotrypsin
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Curemark
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase III, open label extension study evaluating the continued safety and efficacy of CM-AT in pediatric patients with autism with all levels of fecal chymotrypsin.
Who can join: Review the eligibility criteria below.
Location: Southwest Autism Research & Resource Center (S.A.R.R.C.) — Phoenix, Arizona
Age range: 3 Years to 17 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (31 Sites)
Showing the first 25 of 31 sites.
- Southwest Autism Research & Resource Center (S.A.R.R.C.) — Phoenix, Arizona
- University of Arizona, Pediatrics Multidisciplinary Research Unit — Tucson, Arizona
- Arkansas Children'S Hosp. Research Institute (A.C.H.R.I.) — Little Rock, Arkansas
- N.R.C. Research Institute — Orange, California
- M.I.N.D. Institute (Univ.of California, Davis) — Sacramento, California
- University of California (U.C.S.F.) — San Francisco, California
- IMMUNOe Research Centers — Centennial, Colorado
- Yale Child Study Center — New Haven, Connecticut
- Segal Institute For Clinical Research — North Miami, Florida
- Advent Health -Lake Mary Pediatrics — Orange City, Florida
- A.P.G. Research — Orlando, Florida
- Research Institute of Deaconess Clinic — Newburgh, Indiana
- Lake Charles Clinical Trials — Lake Charles, Louisiana
- L.S.U. Health Sciences Center — Shreveport, Louisiana
- Detroit Clinical Research Center, P.C. — Bingham Farms, Michigan
- Children'S Specialized Hospital — Egg Harbor, New Jersey
- Children's Specialized Hospital — Toms River, New Jersey
- Clinical Research Center of Nj — Voorhees Township, New Jersey
- Lovelace Scientific Resources — Albuquerque, New Mexico
- Richmond Behavioral Associates — Staten Island, New York
- Montefiore Med.Cneter, Autism & Obsessive Compulsive Spectrum Program — The Bronx, New York
- Duke Center For Autism and Brain Development — Durham, North Carolina
- Cleveland Clinic Autism Center — Cleveland, Ohio
- Omega Medical Research — Warwick, Rhode Island
- Carolina Clinical Trials, Inc. — Charleston, South Carolina
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.