Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (NCT02659241)
A Pilot Study of Wee1 Inhibition Induction Prior to Tumor Reductive Surgery in Ovarian Cancer
๐ฉบ Plain-English Summary (8th-Grade Level)
This pilot early phase I trial studies how adavosertib affects the tumor deoxyribonucleic acid (DNA) of patients undergoing surgery for high grade (fast growing or aggressive) ovarian, fallopian tube, or primary peritoneal cancer that has spread to other places in the body (advanced). Certain characteristics in the DNA of these patients may affect how well they respond to treatment. Learning how adavosertib affects DNA in tumor cells may help doctors plan effective treatment.
Who can join: Review the eligibility criteria below.
Location: OHSU Knight Cancer Institute โ Portland, Oregon
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (8 Sites)
- OHSU Knight Cancer Institute โ Portland, Oregon
- MD Anderson in The Woodlands โ Conroe, Texas
- Memorial Hermann Memorial City Medical Center โ Houston, Texas
- M D Anderson Cancer Center โ Houston, Texas
- The Woman's Hospital of Texas โ Houston, Texas
- MD Anderson West Houston โ Houston, Texas
- MD Anderson League City โ League City, Texas
- MD Anderson in Sugar Land โ Sugar Land, Texas
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Fallopian Tube Carcinoma
- Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1 โ Buffalo, New York
- Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors โ Bethesda, Maryland
- Folate Receptor Alpha Dendritic Cells (FRฮฑDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial โ Scottsdale, Arizona
Explore by condition: All Advanced Fallopian Tube Carcinoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.