Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia (NCT02665065)
A Multicenter, Pivotal Phase 3 Study of Iomab-B Prior to Allogeneic Hematopoietic Cell Transplant Versus Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia (AML)
๐ฉบ Plain-English Summary (8th-Grade Level)
The primary objective of this study is to demonstrate the efficacy of Iomab-B, in conjunction with a Reduced Intensity Conditioning (RIC) regimen and protocol-specified allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid Leukemia (AML).
Who can join: Review the eligibility criteria below.
Location: Banner MD Anderson Cancer Center โ Gilbert, Arizona
Age range: 55 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (24 Sites)
- Banner MD Anderson Cancer Center โ Gilbert, Arizona
- Yale Cancer Center โ New Haven, Connecticut
- Georgetown University Medical Center โ Washington D.C., District of Columbia
- Mayo Clinic โ Jacksonville, Florida
- Loyola University Medical Center โ Maywood, Illinois
- University of Iowa โ Iowa City, Iowa
- The University of Kansas Cancer Center โ Westwood, Kansas
- Mayo Clinic โ Rochester, Minnesota
- Washington University School of Medicine โ St Louis, Missouri
- University of Nebraska Medical Center โ Omaha, Nebraska
- Roswell Park Cancer Institute โ Buffalo, New York
- Weill Cornell Medicine โ New York, New York
- Memorial Sloan Kettering Cancer Center โ New York, New York
- Stony Brook University โ Stony Brook, New York
- University of North Carolina Hospital โ Chapel Hill, North Carolina
- University Hospital of Cleveland Seidman Cancer Center โ Cleveland, Ohio
- The Ohio State University Comprehensive Cancer Center โ Columbus, Ohio
- Oregon Health & Science University โ Portland, Oregon
- Baylor Charles A. Sammons Cancer Center โ Dallas, Texas
- MD Anderson Cancer Center โ Houston, Texas
- Fred Hutchinson Cancer Research Center โ Seattle, Washington
- Medical College of Wisconsin โ Milwaukee, Wisconsin
- University of Ottawa โ Ottawa, Ontario
- Princess Margaret Cancer Centre โ Toronto, Ontario
๐ Contact the Study Coordinator
Phone: (877) 632-6789
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Myeloid Leukemia
- PRGN-3006 Adoptive Cellular Therapy for CD33-Positive Relapsed or Refractory AML, MRD Positive AML or Higher Risk MDS โ Tampa, Florida
- Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCT โ Tampa, Florida
- Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy โ Little Rock, Arkansas
- Azacitidine and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia โ Burbank, California
- A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies โ Duarte, California
- A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia โ Madera, California
Explore by condition: All Acute Myeloid Leukemia clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.