Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension (NCT02682511)
A Phase 2 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of Ifetroban in Patients With Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension (SSc-PAH)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this phase 2 multicenter, randomized, double-blind, placebo-controlled, study is to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic SSc (dcSSc) or SSc-associated pulmonary arterial hypertension (SSc-PAH).
Who can join: Review the eligibility criteria below.
Location: The Universtity of Arizona Arthrtis Center — Tucson, Arizona
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (13 Sites)
- The Universtity of Arizona Arthrtis Center — Tucson, Arizona
- UCLA — Los Angeles, California
- Cleveland Clinic - Florida — Weston, Florida
- Johns Hopkins University — Baltimore, Maryland
- Massachusetts General Hospital — Boston, Massachusetts
- University of Nebraska Medical Center — Omaha, Nebraska
- Hospital for Special Surgery — New York, New York
- Thomas Jefferson University — Philadelphia, Pennsylvania
- Medical University of South Carolina — Charleston, South Carolina
- Baylor Research Institute — Dallas, Texas
- PGIMER — Chandigarh, Chandigarh
- KDH - Kokilaben Dhirubhai Ambani Hospital — Mumbai, Maharashtra
- B. J. Government Medical College — Pune, Maharashtra
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.