Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS) (NCT02764541)
Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS): A Randomized Phase II Study of Palbociclib With Letrozole Versus Letrozole Alone for Invasive Lobular Carcinoma and Invasive Ductal Carcinoma
🩺 Plain-English Summary (8th-Grade Level)
This research study is evaluating how well Breast Cancer responds to preoperative treatment with Endocrine treatment in combination with a drug called Palbociclib or Endocrine treatment alone as possible treatments for Hormone Receptor Positive Breast Cancer.
Who can join: Review the eligibility criteria below.
Location: Stamford Hospital — Stamford, Connecticut
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (11 Sites)
- Stamford Hospital — Stamford, Connecticut
- Eastern Maine Medical Center — Brewer, Maine
- Dana-Farber at St. Elizabeth's Medical Center — Boston, Massachusetts
- Beth Israel Deaconess Medical Center — Boston, Massachusetts
- Dana-Farber Cancer Institute — Boston, Massachusetts
- DF/BWCC at Milford Regional Medical Center — Milford, Massachusetts
- DF/BWCC in clinical affiliation with South Shore Hospital — South Weymouth, Massachusetts
- Lifespan — Providence, Rhode Island
- Sarah Cannon Research Institute — Nashville, Tennessee
- Vanderbilt University Medical Center — Nashville, Tennessee
- MD Anderson Cancer Center — Houston, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.