Pediatric ACL: Understanding Treatment Options (NCT02772770)
Pediatric ACL: Understanding Treatment Options (PLUTO)
🩺 Plain-English Summary (8th-Grade Level)
Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four operative treatments including (1) transphyseal ACL reconstruction (2) partial transphyseal ACL reconstruction, (3) physeal-sparing epiphyseal ACL reconstruction using the Anderson technique, and (4) physeal-sparing ACL reconstruction using the Micheli/Kocher technique in prepubescent and pubescent skeletally immature patients.
Who can join: Review the eligibility criteria below.
Location: Stanford University Medical Center — Palo Alto, California
Age range: 5 Years to 18 Years
🧪 Interventions in This Study
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions (OTHER)
- Surgical technique: Transphyseal reconstruction (PROCEDURE)
- Surgical technique: Partial transphyseal reconstruction (PROCEDURE)
- Surgical technique: Physeal sparing reconstruction by the Anderson method (PROCEDURE)
- Surgical technique: Physeal sparing reconstruction by the Micheli/Kocher method (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- Stanford University Medical Center — Palo Alto, California
- Rady Children's Hospital — San Diego, California
- Children's Healthcare of Atlanta — Atlanta, Georgia
- Boston Children's Hospital — Boston, Massachusetts
- Washington University at St. Louis — St Louis, Missouri
- Hospital for Special Surgery — New York, New York
- Cincinnati Children's Medical Center — Cincinnati, Ohio
- Cleveland Clinic Foundation — Cleveland, Ohio
- Children's Hospital of Philadelphia — Philadelphia, Pennsylvania
- Tennessee Orthopaedic Alliance — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.