๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-03

Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery (NCT02775851)

A Phase II and Pilot Trial of PD-1 Blockade With Pembrolizumab (MK-3475) in Patients With Resectable or Unresectable Desmoplastic Melanoma (DM)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This pilot phase II trial studies how well pembrolizumab works in treating patients with desmoplastic melanoma (DM) that can be removed by surgery (resectable) or cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Who can join: Review the eligibility criteria below.

Location: Fairbanks Memorial Hospital โ€” Fairbanks, Alaska

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (280 Sites)

Showing the first 25 of 280 sites.

  • Fairbanks Memorial Hospital โ€” Fairbanks, Alaska
  • Cancer Center at Saint Joseph's โ€” Phoenix, Arizona
  • Mercy Hospital Fort Smith โ€” Fort Smith, Arkansas
  • CHI Saint Vincent Cancer Center Hot Springs โ€” Hot Springs, Arkansas
  • Mission Hope Medical Oncology - Arroyo Grande โ€” Arroyo Grande, California
  • City of Hope Comprehensive Cancer Center โ€” Duarte, California
  • Epic Care-Dublin โ€” Dublin, California
  • Bay Area Breast Surgeons Inc โ€” Emeryville, California
  • Epic Care Partners in Cancer Care โ€” Emeryville, California
  • Los Angeles General Medical Center โ€” Los Angeles, California
  • USC / Norris Comprehensive Cancer Center โ€” Los Angeles, California
  • UCLA / Jonsson Comprehensive Cancer Center โ€” Los Angeles, California
  • Contra Costa Regional Medical Center โ€” Martinez, California
  • USC Norris Oncology/Hematology-Newport Beach โ€” Newport Beach, California
  • Alta Bates Summit Medical Center - Summit Campus โ€” Oakland, California
  • Bay Area Tumor Institute โ€” Oakland, California
  • Keck Medical Center of USC Pasadena โ€” Pasadena, California
  • Pacific Central Coast Health Center-San Luis Obispo โ€” San Luis Obispo, California
  • Mission Hope Medical Oncology - Santa Maria โ€” Santa Maria, California
  • City of Hope South Pasadena โ€” South Pasadena, California
  • City of Hope Upland โ€” Upland, California
  • Epic Care Cyberknife Center โ€” Walnut Creek, California
  • Rocky Mountain Cancer Centers-Aurora โ€” Aurora, Colorado
  • The Medical Center of Aurora โ€” Aurora, Colorado
  • Boulder Community Foothills Hospital โ€” Boulder, Colorado

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—