๐๏ธ Verified NIH Record โข Updated 2026-03-02
A Pilot Surgical Trial To Evaluate Early Immunologic Pharmacodynamic Parameters For The PD-1 Checkpoint Inhibitor, Pembrolizumab (MK-3475), In Patients With Surgically Accessible Recurrent/Progressive Glioblastoma (NCT02852655)
๐ต Active, Not Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Dana-Farber Cancer Institute
๐ฉบ Plain-English Summary (8th-Grade Level)
This research study is studying an immunotherapy as a possible treatment for Glioblastoma.
Who can join: Review the eligibility criteria below.
Location: University of California, Los Angeles โ Los Angeles, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (7 Sites)
- University of California, Los Angeles โ Los Angeles, California
- University of California, San Francisco โ San Francisco, California
- Massachusetts General Hospital โ Boston, Massachusetts
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Memorial Sloan-Kettering Cancer โ New York, New York
- UT, MD Anderson Cancer Center โ Houston, Texas
- Huntsman Cancer Institute โ Salt Lake City, Utah
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Brain Cancer
- Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and Caregivers โ Detroit, Michigan
- Pilot Study of Optune (NovoTTF-100A) for Recurrent Atypical and Anaplastic Meningioma โ Los Angeles, California
- Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker โ Lebanon, New Hampshire
- A First in Human Study Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers for Malignant Brain Tumors โ New York, New York
- Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors. โ Cincinnati, Ohio
Explore by condition: All Brain Cancer clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.