๐๏ธ Verified NIH Record โข Updated 2026-07-17
Pembrolizumab In Central Nervous System Metastases (NCT02886585)
Phase II Trial of Pembrolizumab in Central Nervous System Metastases From Multiple Histologies
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Massachusetts General Hospital
๐ฉบ Plain-English Summary (8th-Grade Level)
This research study is studying Pembrolizumab as a possible treatment for this diagnosis for metastases in the central nervous system (brain and spinal cord).
Who can join: Review the eligibility criteria below.
Location: Massachusetts General Hospital โ Boston, Massachusetts
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (2 Sites)
- Massachusetts General Hospital โ Boston, Massachusetts
- Dana Farber Cancer Institute โ Boston, Massachusetts
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Brain Metastases
- Preop fSRS for Resectable Brain Metastases โ Tampa, Florida
- Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases โ Washington D.C., District of Columbia
- Study Assessing QBS72S For Treating Brain Metastases โ Palo Alto, California
- A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for Detecting True-versus Pseudo-Progression of Brain Metastases on Immunotherapy โ Houston, Texas
- Neurocognitive Decline in Patients With Brain Metastases โ Dallas, Texas
- MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases โ Durham, North Carolina
Explore by condition: All Brain Metastases clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.