Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma (MM) (NCT02899052)
A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma
π©Ί Plain-English Summary (8th-Grade Level)
A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in participants with relapsed or refractory MM and have received 1 to 3 prior lines of therapy. Part 4 of this study is currently enrolling.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham - Main /ID# 151405 β Birmingham, Alabama
Age range: 18 Years
π§ͺ Interventions in This Study
π "Do I Qualify?" β 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria β
π All Participating Trial Locations (32 Sites)
Showing the first 25 of 32 sites.
- University of Alabama at Birmingham - Main /ID# 151405 β Birmingham, Alabama
- University of Arkansas for Medical Sciences /ID# 151399 β Little Rock, Arkansas
- Memorial Healthcare System /ID# 224862 β Hollywood, Florida
- Winship Cancer Institute of Emory University /ID# 161710 β Atlanta, Georgia
- The University of Chicago Medical Center /ID# 151395 β Chicago, Illinois
- Indiana Blood & Marrow Transpl /ID# 218862 β Indianapolis, Indiana
- Duplicate_University of Kentucky Chandler Medical Center /ID# 151407 β Lexington, Kentucky
- Central Maine Medical Center /ID# 218856 β Lewiston, Maine
- Duplicate_University of Maryland School of Medicine /ID# 159721 β Baltimore, Maryland
- Oncology Hematology Associates (OHA) - Springfield /ID# 218855 β Springfield, Missouri
- Washington University-School of Medicine /ID# 222651 β St Louis, Missouri
- Duke Cancer Center /ID# 162062 β Durham, North Carolina
- University of Pennsylvania /ID# 151768 β Philadelphia, Pennsylvania
- University of Texas Southwestern Medical Center /ID# 218336 β Dallas, Texas
- Baylor Scott & White Medical Center- Temple /ID# 218252 β Temple, Texas
- University of Utah /ID# 151397 β Salt Lake City, Utah
- Duplicate_VA Puget Sound Healthcare Syst /ID# 155369 β Seattle, Washington
- Aurora Health Care, Aurora Cancer Center /ID# 209612 β Wauwatosa, Wisconsin
- Border Medical Oncology Research Unit Albury Wodonga Regiona /ID# 222200 β East Albury, New South Wales
- Calvary Mater Newcastle /ID# 218739 β Waratah, New South Wales
- Flinders Medical Centre /ID# 221345 β Bedford Park, South Australia
- Royal Hobart Hospital /ID# 217546 β Hobart, Tasmania
- Debreceni Egyetem-Klinikai Kozpont /ID# 217624 β Debrecen, HajdΓΊ-Bihar
- Semmelweis Egyetem /ID# 217626 β Budapest,
- Del-pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet /ID# 217625 β Budapest,
π° Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant β Tampa, Florida
- MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb β Beverly Hills, California
- A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refractory Multiple Myeloma β Phoenix, Arizona
- A Study of Carfilzomib, Lenalidomide, Vorinostat, and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma β Hackensack, New Jersey
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π‘ How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.