πŸ›οΈ Verified NIH Record β€’ Updated 2025-08-01

Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma (MM) (NCT02899052)

A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

πŸ”΅ Active, Not Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: AbbVie

🩺 Plain-English Summary (8th-Grade Level)

A Phase 2, open-label, dose escalation study to evaluate the safety and efficacy of venetoclax in combination with carfilzomib-dexamethasone (Kd) in participants with relapsed or refractory MM and have received 1 to 3 prior lines of therapy. Part 4 of this study is currently enrolling.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham - Main /ID# 151405 β€” Birmingham, Alabama

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (32 Sites)

Showing the first 25 of 32 sites.

  • University of Alabama at Birmingham - Main /ID# 151405 β€” Birmingham, Alabama
  • University of Arkansas for Medical Sciences /ID# 151399 β€” Little Rock, Arkansas
  • Memorial Healthcare System /ID# 224862 β€” Hollywood, Florida
  • Winship Cancer Institute of Emory University /ID# 161710 β€” Atlanta, Georgia
  • The University of Chicago Medical Center /ID# 151395 β€” Chicago, Illinois
  • Indiana Blood & Marrow Transpl /ID# 218862 β€” Indianapolis, Indiana
  • Duplicate_University of Kentucky Chandler Medical Center /ID# 151407 β€” Lexington, Kentucky
  • Central Maine Medical Center /ID# 218856 β€” Lewiston, Maine
  • Duplicate_University of Maryland School of Medicine /ID# 159721 β€” Baltimore, Maryland
  • Oncology Hematology Associates (OHA) - Springfield /ID# 218855 β€” Springfield, Missouri
  • Washington University-School of Medicine /ID# 222651 β€” St Louis, Missouri
  • Duke Cancer Center /ID# 162062 β€” Durham, North Carolina
  • University of Pennsylvania /ID# 151768 β€” Philadelphia, Pennsylvania
  • University of Texas Southwestern Medical Center /ID# 218336 β€” Dallas, Texas
  • Baylor Scott & White Medical Center- Temple /ID# 218252 β€” Temple, Texas
  • University of Utah /ID# 151397 β€” Salt Lake City, Utah
  • Duplicate_VA Puget Sound Healthcare Syst /ID# 155369 β€” Seattle, Washington
  • Aurora Health Care, Aurora Cancer Center /ID# 209612 β€” Wauwatosa, Wisconsin
  • Border Medical Oncology Research Unit Albury Wodonga Regiona /ID# 222200 β€” East Albury, New South Wales
  • Calvary Mater Newcastle /ID# 218739 β€” Waratah, New South Wales
  • Flinders Medical Centre /ID# 221345 β€” Bedford Park, South Australia
  • Royal Hobart Hospital /ID# 217546 β€” Hobart, Tasmania
  • Debreceni Egyetem-Klinikai Kozpont /ID# 217624 β€” Debrecen, HajdΓΊ-Bihar
  • Semmelweis Egyetem /ID# 217626 β€” Budapest,
  • Del-pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet /ID# 217625 β€” Budapest,

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—