๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-12-03

Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment (NCT02932280)

A Phase I/II Study of Neratinib in Pediatric Patients With Relapsed or Refractory Solid Tumors

๐Ÿ”ต Active, Not Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to test the safety of neratinib at different dose levels and to find out what effects, good and bad, it has on the patients and the cancer.

Who can join: Review the eligibility criteria below.

Location: Phoenix Children'S Hospital โ€” Phoenix, Arizona

Age range: 3 Years to 21 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (9 Sites)

  • Phoenix Children'S Hospital โ€” Phoenix, Arizona
  • Arkansas Children's Hospital โ€” Little Rock, Arkansas
  • Stanford University School of Medicine and Stanford Cancer Institute โ€” Palo Alto, California
  • Arnold Palmer Hospital for Children โ€” Orlando, Florida
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Pennsylvania State Hershey Children's Hospital โ€” Hershey, Pennsylvania
  • University of Texas โ€” San Antonio, Texas
  • Huntsman Cancer Institue โ€” Salt Lake City, Utah
  • Alberta Children'S Hospital โ€” Calgary, Alberta

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Solid Tumor clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—