๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-09-17

Postoperative and Chronic Pain Genetic Spine Surgery Study (NCT02998138)

A Multi-center Study of Genomic and Psychological Factors Affecting Postoperative and Chronic Pain in Children Undergoing Invasive (Spine) Surgery

๐Ÿ”ต Active, Not Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: Children's Hospital Medical Center, Cincinnati

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This will be an open label, prospective study to determine the association between specific genotypes, epigenetics and behavioral factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic and side effect responses to perioperative opioids, chronic postoperative pain and gene expression in adolescents following major spine surgery.

Who can join: Review the eligibility criteria below.

Location: Stanford University Hospital โ€” Stanford, California

Age range: 10 Years to 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • Stanford University Hospital โ€” Stanford, California
  • Johns Hopkins Hospital โ€” Baltimore, Maryland
  • University of Mississippi Medical Center โ€” Jackson, Mississippi
  • Duke Children's Hospital โ€” Durham, North Carolina
  • The Children's Hospital of Philadelphia โ€” Philadelphia, Pennsylvania

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Scoliosis clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—