A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC) (NCT03006068)
A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects With Ulcerative Colitis
๐ฉบ Plain-English Summary (8th-Grade Level)
This study is designed to evaluate the long-term safety and efficacy of Upadacitinib in participants with ulcerative colitis (UC) who have not responded at the end of the induction period in Study M14-234 Substudy 1, who have had loss of response during the maintenance period of Study M14-234 Substudy 3, or who have successfully completed Study M14-234 Substudy 3.
Who can join: Review the eligibility criteria below.
Location: East View Medical Research, LLC /ID# 171184 โ Mobile, Alabama
Age range: 16 Years to 75 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (492 Sites)
Showing the first 25 of 492 sites.
- East View Medical Research, LLC /ID# 171184 โ Mobile, Alabama
- CB Flock Research Corporation /ID# 165986 โ Mobile, Alabama
- Delsol Research Management, Ll /Id# 170130 โ Chandler, Arizona
- Digestive Disease Consultants, A Division of Arizona Digestive Health, P.C /ID# 211886 โ Mesa, Arizona
- Duplicate_Arizona Arthritis & Rheumatology Research, PLLC /ID# 169823 โ Sun City, Arizona
- Adobe Clinical Research LLC /ID# 155249 โ Tucson, Arizona
- Duplicate_University of Arizona /ID# 150568 โ Tucson, Arizona
- Citrus Valley Gastroenterology /ID# 151915 โ Covina, California
- Newport Huntington Medical Group /ID# 217006 โ Huntington Beach, California
- UC San Diego Health System /ID# 155187 โ La Jolla, California
- United Medical Doctors /ID# 207467 โ Los Alamitos, California
- TLC Clinical Research Inc /ID# 216830 โ Los Angeles, California
- Gastrointestinal Biosciences Clinical Trials, LLC /ID# 157082 โ Los Angeles, California
- Facey Medical Foundation /ID# 203135 โ Mission Hills, California
- United Medical Doctors - Murrieta /ID# 151213 โ Murrieta, California
- Ventura County Gastroenterology Medical Group /ID# 163417 โ Oxnard, California
- Inland Empire Clinical Trials, LLC /ID# 216163 โ Rialto, California
- San Diego Clinical Trials /ID# 212121 โ San Diego, California
- Medical Assoc Research Grp /ID# 169149 โ San Diego, California
- Univ of California San Francis /ID# 164583 โ San Francisco, California
- Delta Waves, Inc. /ID# 151727 โ Colorado Springs, Colorado
- South Denver Gastroenterology /ID# 151224 โ Lone Tree, Colorado
- Western States Clinical Res /ID# 158078 โ Wheat Ridge, Colorado
- Duplicate_Western Connecticut Medical Group /ID# 169211 โ Danbury, Connecticut
- Gastroenterology Center of Connecticut /ID# 150534 โ Hamden, Connecticut
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ulcerative Colitis (UC)
- Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants โ Miami, Florida
- A Long-Term Registry of Humiraยฎ (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC) โ Birmingham, Alabama
- A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis โ Coronado, California
- Using Breath Tests to Study Gut Sulfur Changes During Dietary Therapy โ Kelowna, British Columbia
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis โ Miami, Florida
Explore by condition: All Ulcerative Colitis (UC) clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.