🏛️ Verified NIH Record • Updated 2026-03-27

ADAPT - A Patient Registry of the Real-world Use of Orenitram® (NCT03045029)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: United Therapeutics

🩺 Plain-English Summary (8th-Grade Level)

This prospective, observational, multicenter, patient registry will follow patients who are receiving treatment with Orenitram for the treatment of PAH for up to 78 weeks from Orenitram initiation

Who can join: Review the eligibility criteria below.

Location: University of California - San Francisco — Fresno, California

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (41 Sites)

Showing the first 25 of 41 sites.

  • University of California - San Francisco — Fresno, California
  • University of Southern California - Keck Medical Center — Los Angeles, California
  • Paloma Medical Group — San Juan Capistrano, California
  • Santa Barbara Pulmonary Associates — Santa Barbara, California
  • Harbor UCLA Medical Center — Torrance, California
  • Aurora Denver Cardiology Associates — Aurora, Colorado
  • Pueblo Pulmonary Associates — Pueblo, Colorado
  • Lung Associates PA — Bradenton, Florida
  • University of Florida Clinical Research Center — Gainesville, Florida
  • St. Vincent's Lung, Sleep, and Critical Care Specialists — Jacksonville, Florida
  • AdventHealth Orlando — Orlando, Florida
  • Central Florida Pulmonary Group, P.A. — Orlando, Florida
  • USF South Florida Heart Health — Tampa, Florida
  • Cleveland Clinic Florida — Weston, Florida
  • Piedmont Healthcare/Research — Austell, Georgia
  • Loyola University Chicago — Chicago, Illinois
  • Saint Vincent Hospital and Health Services — Indianapolis, Indiana
  • University Of Iowa Hospital and Clinics — Iowa City, Iowa
  • University of Louisville Physicians Outpatient Center — Louisville, Kentucky
  • Chest Medicine Associates — South Portland, Maine
  • Mclaren Greater Lansing — Okemos, Michigan
  • Beaumont Hospital Troy — Troy, Michigan
  • University of Nebraska Medical Center — Omaha, Nebraska
  • Albany Medical College — Albany, New York
  • New York Methodist Hospital — Brooklyn, New York

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗