🏛️ Verified NIH Record • Updated 2025-12-01
Role of Metformin on Muscle Health of Older Adults (NCT03107884)
Metformin to Prevent Inactivity-induced Loss of Muscle Health During Aging
🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic Sponsor: University of Utah
🩺 Plain-English Summary (8th-Grade Level)
Muscle atrophy and insulin resistance are common after bed rest in healthy older adults. Metformin treatment has been shown to improve insulin sensitivity and attenuate muscle loss in insulin resistance adults though the mechanisms are not fully known. Metformin used as a preventive strategy to maintain muscle and metabolic health in bed ridden older adults has not been investigated.
Who can join: Review the eligibility criteria below.
Location: University of Utah — Salt Lake City, Utah
Age range: 60 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Utah — Salt Lake City, Utah
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Muscle Atrophy
- Neuromodulation for Prevention of Intensive Care Unit Acquired Weakness and Post Intensive Care Syndrome — Houston, Texas
- FIT Exercise in 30d of ULLS-induced Muscle Disuse — Lexington, Kentucky
- Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis. — Irvine, California
Explore by condition: All Muscle Atrophy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.