MCI: CPAP Treatment of OSA (Memories2) (NCT03113461)
Changing the Trajectory of Mild Cognitive Impairment With CPAP Treatment of Obstructive Sleep Apnea
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive Impairment (MCI) as measured by cognitive testing, and brain magnetic resonance imaging (MRI) scans. Study participants will be assessed at baseline, six-month (cognitive tests only) and one-year follow-up.
Who can join: Review the eligibility criteria below.
Location: Washington University in St. Louis โ St Louis, Missouri
Age range: 55 Years to 85 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (4 Sites)
- Washington University in St. Louis โ St Louis, Missouri
- University of Pennsylvania โ Philadelphia, Pennsylvania
- University of Texas at Austin โ Austin, Texas
- University of Virginia โ Charlottesville, Virginia
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mild Cognitive Impairment
- Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment โ Toronto, Ontario
- Remote Game-based Exercise Program for Cognitive and Motor Function Improvement โ Los Angeles, California
- Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD) โ Boston, Massachusetts
- Glutathione in Mild Cognitive Impairment โ Houston, Texas
- Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Standard of Care Monoclonal Antibody (mAb) Therapy โ Morgantown, West Virginia
- Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease โ Los Angeles, California
Explore by condition: All Mild Cognitive Impairment clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.