A Study of Memory, Thinking, and Brain Imaging in Adults With Histiocytosis (NCT03127709)
A Clinical, Structural, and Functional Neuroimaging Study of Cognition in Adults With Erdheim-Chester Disease, Langerhans Cell Histiocytosis, Rosai-Dorfman Disease, and Other Histiocytoses
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to try to understand how histopcytosis can cause symptoms or problems in the brain. The tests being done in the study will look at memory and thinking as well as brain function via MRI scan.
Who can join: Review the eligibility criteria below.
Location: Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey
Age range: 18 Years
🧪 Interventions in This Study
- Trail Making Test, Parts A & B (BEHAVIORAL)
- Brief Test of Attention (BEHAVIORAL)
- Symbol Span (BEHAVIORAL)
- Controlled Oral Word Association Test (BEHAVIORAL)
- The Hopkins Verbal Learning Test-Revised (BEHAVIORAL)
- Brief Visuospatial Memory Test-Revised (BEHAVIORAL)
- Hospital Anxiety and Depression Scale (BEHAVIORAL)
- McGill Quality of Life Scale (BEHAVIORAL)
- MR Brain Imaging (DIAGNOSTIC_TEST)
- Resting state functional MRI (DIAGNOSTIC_TEST)
- Functional Assessment of Cancer Therapy Cognitive Scale (FACT-Cog) (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey
- Memorial Sloan Kettering Monmouth — Middletown, New Jersey
- Memorial Sloan Kettering Cancer Center @ Suffolk — Commack, New York
- Memorial Sloan Kettering Westchester — Harrison, New York
📞 Contact the Study Coordinator
Phone: (800) 525-2225
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Histiocytosis
- Histiocytic Disorder Follow-up Study — Birmingham, Alabama
Explore by condition: All Histiocytosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.