๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-09-25

Palbociclib After CDK and Endocrine Therapy (PACE) (NCT03147287)

Palbociclib After CDK and Endocrine Therapy (PACE): A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab for Endocrine Pre-treated ER+/HER2- Metastatic Breast Cancer

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Dana-Farber Cancer Institute

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This research study is studying three combinations of drugs as treatments for breast cancer. The drugs involved in this study are: -Fulvestrant -Fulvestrant with Palbociclib -Fulvestrant with Palbociclib and Avelumab

Who can join: Review the eligibility criteria below.

Location: University of Miami โ€” Miami, Florida

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (22 Sites)

  • University of Miami โ€” Miami, Florida
  • Emory University - Winship Cancer Institute โ€” Atlanta, Georgia
  • Northwestern University โ€” Chicago, Illinois
  • Indiana University โ€” Indianapolis, Indiana
  • The University of Kansas Cancer Center - North โ€” Kansas City, Kansas
  • The University of Kansas Cancer Center - Overland Park โ€” Overland Park, Kansas
  • The University of Kansas Cancer Center โ€” Westwood, Kansas
  • University of Louisville โ€” Louisville, Kentucky
  • Eastern Maine Medical Center โ€” Bangor, Maine
  • Boston Medical Center โ€” Boston, Massachusetts
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • Dana-Farber at St. Elizabeth's Medical Center โ€” Brighton, Massachusetts
  • DF/BWCC at Milford Regional Medical Center โ€” Milford, Massachusetts
  • DF/BWCC in clinical affiliation with South Shore Hospital โ€” South Weymouth, Massachusetts
  • The University of Kansas Cancer Center - Lee's Summit โ€” Lee's Summit, Missouri
  • Washington University โ€” St Louis, Missouri
  • Dana-Farber/New Hampshire Oncology-Hematology โ€” Londonderry, New Hampshire
  • University of North Carolina at Chapel Hill โ€” Chapel Hill, North Carolina
  • University of Pennsylvania โ€” Philadelphia, Pennsylvania
  • Vanderbilt University Medical Center โ€” Nashville, Tennessee
  • Baylor University โ€” Houston, Texas
  • Aurora Cancer Care โ€” Milwaukee, Wisconsin

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—